An update on myofibromas and myofibromatosis affecting the oral regions with report of 24 new cases

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Molly Housley SmithIndraneel Bhattacharyya

Abstract

Myofibromas are uncommon soft tissue tumors exhibiting considerable histopathologic overlap with other benign and malignant entities. The treatment of lesions arising in the oral cavity is controversial. Here, we present 24 new cases and review the literature. A search for oral myofibromas was performed within the archives of the University of Florida Oral Pathology and Surgical Pathology Services (1994-2015). Demographic information and immunohistochemical results were recorded. MEDLINE and Web of Science were searched for reports of myofibroma of the oral cavity and oropharynx published in the English-language literature between January 1990 and July 2016, and the results were analyzed. In total, 245 cases were identified: 24 from our present series and 221 from the literature. The distribution by gender was 54.6% male and 45.4% female, and the mean age was 23.1 years. Only 7 patients had known multiple lesions. Treatment modalities varied greatly. Of those with follow-up information, only 9 were cases with recurrences. Myofibromas may resemble several other entities. Because of the potential for multiple (perhaps visceral) lesions and the possibility of overtreatment, accurate diagnosis is of utmost importance. Reports of ca...Continue Reading

Citations

Feb 13, 2020·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Elisa Carvalho de SiqueiraCarolina Cavaliéri Gomes
Apr 27, 2020·Head and Neck Pathology·John Lennon Silva CunhaRicardo Luiz Cavalcanti de Albuquerque-Júnior
Jul 10, 2017·Head and Neck Pathology·Molly Housley SmithSarah G Fitzpatrick
Aug 11, 2020·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Maram BawazirDonald M Cohen
May 8, 2021·BMJ Case Reports·Vindhya SavithriThara Aravind

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
M W LingenD B Solt
Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Marilena VeredDan Dayan
Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
A C JonesS M Kerpel
Oral Surgery, Oral Medicine, and Oral Pathology
S D VincentM W Finkelstein
© 2022 Meta ULC. All rights reserved