An update on radiation therapy in head and neck cancers

Expert Review of Anticancer Therapy
Rosario MazzolaFilippo Alongi

Abstract

Technological and technical improvements allowed for significant advances in the field of radiation therapy (RT) of head and neck cancer (HNC). Several organ-sparing strategies have been investigated with the objective to decrease acute and long-term adverse effects and, subsequently, to assure a better quality of life in patients affected by HNC. In this context, intensity modulated irradiation and the use of multimodality-imaging could help clinicians to obtain a rapid dose fall off towards surrounding healthy tissues and a better delineation of targets volumes and organs at risk. Areas covered: A literature review was performed with the aim to offer an update on radiation therapy in HNC. Expert commentary: During these last years, radiation oncologists have observed a continuous changing regarding radiation treatment for HNC. The adoption of intensity-modulated RT (IMRT) and the use of multimodality-imaging for tumor volume definition and organs at risk or delineation have improved the clinical outcomes of HNC patients. In the future, a better integration of functional imaging for target volume delineation as well as adaptive delivery strategies will allow to further personalize radiation oncology in HNC. Furthermore, the la...Continue Reading

References

Mar 28, 2002·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·H BartelinkM van Glabbeke
Dec 14, 2004·International Journal of Radiation Oncology, Biology, Physics·Avraham EisbruchAlfons J M Balm
Sep 13, 2005·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Mary FengAvraham Eisbruch
Nov 1, 2005·International Journal of Radiation Oncology, Biology, Physics·Eric K HansenPing Xia
Apr 22, 2006·International Journal of Radiation Oncology, Biology, Physics·Adam C RiegelPing S Wong
Mar 24, 2007·International Journal of Radiation Oncology, Biology, Physics·Surjeet PoharDavid Feiglin
Nov 1, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Michael K M KamAnthony T C Chan
Dec 2, 2009·Nature Reviews. Clinical Oncology·Marco Durante, Jay S Loeffler
Feb 5, 2010·The Lancet Oncology·Piet Dirix, Sandra Nuyts
Mar 27, 2010·International Journal of Radiation Oncology, Biology, Physics·Shreerang A BhideChristopher M Nutting
Apr 14, 2010·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Pierre CastadotVincent Grégoire
Feb 11, 2011·International Journal of Radiation Oncology, Biology, Physics·Francesco RicchettiGiuseppe Sanguineti
Nov 1, 2011·International Journal of Radiation Oncology, Biology, Physics·Anuradha ThiagarajanNancy Lee
Oct 2, 2012·Clinical Oncology : a Journal of the Royal College of Radiologists·J YooC Walker-Dilks
Feb 12, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Antonetta C HouwelingUulke A van der Heide
Dec 18, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Gustavo Nader MartaRachel Riera
Dec 20, 2013·International Journal of Radiation Oncology, Biology, Physics·Aafke C KraanMischa S Hoogeman
Apr 24, 2014·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Maria Luisa BelliGiovanni Mauro Cattaneo
Sep 19, 2014·World Journal of Gastrointestinal Oncology·Víctor M Castellano-MegíasFrancisco Colina-Ruizdelgado
Sep 10, 2015·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Vincent GrégoireSandra Nuyts
Nov 20, 2015·International Journal of Radiation Oncology, Biology, Physics·Bhishamjit S CheraWilliam Mendenhall
Dec 15, 2015·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C M L DriessenC M L van Herpen
Apr 17, 2016·International Journal of Radiation Oncology, Biology, Physics·G Brandon GunnSteven J Frank
May 15, 2016·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Steven van de WaterMischa S Hoogeman
Sep 10, 2016·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Jacob H RasmussenBarbara M Fischer
Jun 16, 2017·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Stefano UrsinoFrank Lohr
Aug 2, 2017·The Lancet Oncology·Benjamin LacasUNKNOWN MARCH Collaborative Group
Sep 5, 2017·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·P Blanchard, S J Frank
Oct 28, 2017·European Journal of Nuclear Medicine and Molecular Imaging·Antti SilvoniemiHeikki Minn

❮ Previous
Next ❯

Citations

Jun 17, 2020·Frontiers in Oncology·Tania Crombet RamosNormando E Iznaga Escobar
Jul 3, 2021·Journal of Clinical Medicine·Wakako YatsuokaYasuhito Uezono
Aug 1, 2020·Reviews on Recent Clinical Trials·Areti GkantaifiMaria Tolia

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Related Papers

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Vincent GrégoireSandra Nuyts
Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
Vincent Grégoire, Philippe Maingon
© 2022 Meta ULC. All rights reserved