An update on the Society for Immunotherapy of Cancer consensus statement on tumor immunotherapy for the treatment of cutaneous melanoma: version 2.0

Journal for Immunotherapy of Cancer
Ryan J SullivanH L Kaufman

Abstract

Cancer immunotherapy has been firmly established as a standard of care for patients with advanced and metastatic melanoma. Therapeutic outcomes in clinical trials have resulted in the approval of 11 new drugs and/or combination regimens for patients with melanoma. However, prospective data to support evidence-based clinical decisions with respect to the optimal schedule and sequencing of immunotherapy and targeted agents, how best to manage emerging toxicities and when to stop treatment are not yet available. To address this knowledge gap, the Society for Immunotherapy of Cancer (SITC) Melanoma Task Force developed a process for consensus recommendations for physicians treating patients with melanoma integrating evidence-based data, where available, with best expert consensus opinion. The initial consensus statement was published in 2013, and version 2.0 of this report is an update based on a recent meeting of the Task Force and extensive subsequent discussions on new agents, contemporary peer-reviewed literature and emerging clinical data. The Academy of Medicine (formerly Institute of Medicine) clinical practice guidelines were used as a basis for consensus development with an updated literature search for important studies p...Continue Reading

References

Jan 1, 1996·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J M KirkwoodR H Blum
Nov 24, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M B AtkinsS A Rosenberg
Jun 16, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J M KirkwoodR H Blum
Apr 2, 2002·Journal of Immunotherapy·Lisa M GuirguisDouglas J Schwartzentruber
Jul 3, 2003·Journal of the National Cancer Institute
Jul 30, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Axel HauschildReinhard Dummer
Mar 12, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·John M KirkwoodUNKNOWN Eastern Cooperative Oncology Group
Mar 28, 2006·Seminars in Radiation Oncology·James C YangRichard Sherry
Nov 26, 2009·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Jedd D WolchokF Stephen Hodi
Jan 6, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Axel HauschildClaus Garbe
Jun 8, 2010·The New England Journal of Medicine·F Stephen HodiWalter J Urba
Jun 7, 2011·The New England Journal of Medicine·Paul B ChapmanUNKNOWN BRIM-3 Study Group
Jun 7, 2011·The New England Journal of Medicine·Caroline RobertJedd D Wolchok
Nov 8, 2011·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Alexander M M EggermontAlan Spatz
Mar 30, 2012·The Lancet Oncology·Kim MargolinF Stephen Hodi
Jun 6, 2012·The New England Journal of Medicine·Keith T FlahertyUNKNOWN METRIC Study Group
Jun 4, 2013·The New England Journal of Medicine·Omid HamidAntoni Ribas
Jun 4, 2013·The New England Journal of Medicine·Jedd D WolchokMario Sznol
Jul 9, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Andrea MaurichiMario Santinami
Sep 30, 2014·The New England Journal of Medicine·James LarkinAntoni Ribas
Nov 5, 2014·JAMA : the Journal of the American Medical Association·F Stephen HodiJohn M Kirkwood
Nov 18, 2014·The New England Journal of Medicine·Caroline RobertDirk Schadendorf
Nov 18, 2014·The New England Journal of Medicine·Caroline RobertPaolo A Ascierto
Nov 20, 2014·The New England Journal of Medicine·Alexandra SnyderTimothy A Chan
Jan 8, 2015·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Pedram GeramiJohn F Stone
Feb 11, 2015·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Dirk SchadendorfJedd D Wolchok
Feb 26, 2015·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Michele MaioJedd D Wolchok
Mar 15, 2015·Surgical Oncology Clinics of North America·Gary B DeutschMark B Faries
Apr 22, 2015·The New England Journal of Medicine·Caroline RobertUNKNOWN KEYNOTE-006 investigators
Apr 22, 2015·The New England Journal of Medicine·Michael A PostowF Stephen Hodi
Apr 23, 2015·Journal for Immunotherapy of Cancer·Heinz LäubliAlfred Zippelius
May 28, 2015·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Robert H I AndtbackaRobert S Coffin
Jun 2, 2015·The New England Journal of Medicine·James LarkinJedd D Wolchok
Jun 2, 2015·The New England Journal of Medicine·Dung T LeLuis A Diaz

❮ Previous
Next ❯

Citations

Jan 31, 2019·Journal of Leukocyte Biology·Ricardo A León-LetelierEzequiel M Fuentes-Pananá
Aug 26, 2020·Immunotherapy·Janice HuPaul J Mosca
Aug 16, 2019·Therapeutic Advances in Vaccines and Immunotherapy·Brendon J Coventry
Aug 24, 2018·Journal for Immunotherapy of Cancer·Mark R Albertini
Aug 14, 2019·Applied Microbiology and Biotechnology·Martha Lucia Ruiz BenitezFabiana Kömmling Seixas
May 14, 2020·Melanoma Management·Rachael MillerEmilie Scherrer
Jan 10, 2019·Frontiers in Immunology·Franziska EckertStephan M Huber
Nov 17, 2020·Frontiers in Immunology·Ya-Nan XueWei-Qiang Tan
May 19, 2021·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Neda RahimianHamed Mirzaei
Jul 3, 2021·International Journal of Molecular Sciences·Strahil Strashilov, Angel Yordanov
Dec 27, 2019·The Journal of Investigative Dermatology·Basia M MichalskiEva A Hurst

❮ Previous
Next ❯

Methods Mentioned

BETA
dissection
biopsy
surgical resection

Clinical Trials Mentioned

NCT02224781

Software Mentioned

EndNote
CombiAD
iRECIST
QTWIST

Related Concepts

Related Feeds

Cancer Immunotherapy

Cancer immunotherapy is an important field of research that is looking at controlling cancer and tumor growth by activating the individuals own immune system. Recent studies have utilized chimeric antigen receptor t-cell therapy, immune checkpoint inhibitors and neoantigen vaccines. Discover the latest research on cancer immunotherapy here.

Cancer Vaccines

Cancer vaccines are vaccines that either treat existing cancer or prevent development of a cancer.