An Update on the Status of Current Research on the Mammalian Microbiome

ILAR Journal
Karen E Nelson

Abstract

The microbiome refers to the thousands of microbial species that inhabit a specific host or environment. Extensive microbiome surveys have been conducted for soils, the built environment, and our oceans. In addition, extensive studies of the human microbiome have revealed significant microbial diversity across all body sites and have hinted at new opportunities for diagnostic and therapeutic approaches to addressing human health and disease. Mammals in general are known to hold a complicated mix of species within their gastrointestinal tracts, including virus, archaea, bacteria, and fungi. These microbial species present beneficial aspects to the host species through the production of vitamins, metabolism of plant structural compounds and sugars, and education of the immune system. In addition to a vast number of studies on humans, studies of the mammalian microbiome have been performed, with several publications on a variety of animal species currently available. These have included studies on the microbiome of companion animals, animals used for research, and animals used for agricultural and food purposes, and various human/animal models.

References

Aug 2, 2005·Nature·Marcel MarguliesJonathan M Rothberg
Oct 11, 2005·Nucleic Acids Research·Ross OverbeekVeronika Vonstein
Jun 3, 2006·Science·Steven R GillKaren E Nelson
May 24, 2008·Science·Ruth E LeyJeffrey I Gordon
Feb 3, 2009·Proceedings of the National Academy of Sciences of the United States of America·Jennifer M BrulcBryan A White
May 18, 2011·BMC Microbiology·Regina LamendellaDaniel B Oerther
Jun 16, 2012·Nature·UNKNOWN Human Microbiome Project Consortium
Aug 21, 2012·PLoS Biology·Dirk GeversCurtis Huttenhower
Jun 12, 2013·FEMS Microbiology Ecology·Stuart C SmithJohn P Y Arnould
Jan 5, 2014·PloS One·Tiffanie M NelsonMark V Brown
Jan 15, 2014·PloS One·Aline Rodrigues HoffmannJan S Suchodolski
Aug 31, 2014·Applied and Environmental Microbiology·Marcus H Y LeungPatrick K H Lee
Dec 4, 2014·Systematic and Applied Microbiology·Javad GharechahiGhasem Hosseini Salekdeh
Mar 15, 2015·Applied and Environmental Microbiology·Jinzhen JiaoZhiliang Tan

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Citations

Sep 2, 2015·ILAR Journal·André Bleich, James G Fox
Apr 12, 2019·Frontiers in Microbiology·Jacob G MillsMartin F Breed
Aug 12, 2020·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Raissa Nunes Dos SantosAna Claudia Franco
Sep 12, 2019·Frontiers in Microbiology·Qing TongJian-Tao Zhang

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