An update on the use of massive transfusion protocols in obstetrics

American Journal of Obstetrics and Gynecology
Luis D PachecoGary D V Hankins

Abstract

Obstetrical hemorrhage remains a leading cause of maternal mortality worldwide. New concepts involving the pathophysiology of hemorrhage have been described and include early activation of both the protein C and fibrinolytic pathways. New strategies in hemorrhage treatment include the use of hemostatic resuscitation, although the optimal ratio to administer the various blood products is still unknown. Massive transfusion protocols involve the early utilization of blood products and limit the traditional approach of early massive crystalloid-based resuscitation. The evidence behind hemostatic resuscitation has changed in the last few years, and debate is ongoing regarding optimal transfusion strategies. The use of tranexamic acid, fibrinogen concentrates, and prothrombin complex concentrates has emerged as new potential alternative treatment strategies with improved safety profiles.

References

Jul 20, 2005·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Anneke KweeHein W Bruinse
Jan 12, 2007·The Journal of Trauma·Ernest A GonzalezBruce A McKinley
May 1, 2007·Critical Care : the Official Journal of the Critical Care Forum·Michael Eisenhut
Nov 3, 2007·Current Opinion in Critical Care·Karim BrohiRoss A Davenport
Feb 11, 2009·The Journal of Trauma·Christopher W SnyderJeffrey D Kerby
Jan 12, 2010·Transplantation·Tanja HerrlerKarl-Walter Jauch
Feb 17, 2010·Critical Care : the Official Journal of the Critical Care Forum·Bartolomeu NascimentoSandro Rizoli
Jul 9, 2010·European Journal of Anaesthesiology·Brigitte E Ickx
Jul 16, 2010·Acta Anaesthesiologica Scandinavica·P I JohanssonN H Secher
Jul 29, 2010·Critical Care : the Official Journal of the Critical Care Forum·Nor'azim Mohd YunosJohn Kellum
Nov 5, 2010·The New England Journal of Medicine·Marcel LeviDavid Truloff
Apr 19, 2011·Critical Care : the Official Journal of the Critical Care Forum·Anne-Sophie Ducloy-BouthorsSophie Susen
Jul 28, 2011·Anesthesiology·Brian M GillissMichael A Gropper
Aug 6, 2011·American Journal of Obstetrics and Gynecology·Luis D PachecoGary D V Hankins
Oct 18, 2011·Current Opinion in Critical Care·Neil J Glassford, Rinaldo Bellomo
Mar 15, 2012·Chest·Gordon H GuyattUNKNOWN American College of Chest Physicians Antithrombotic Therapy and Prevention of Thrombosis Panel
Jan 3, 2013·The Journal of Obstetrics and Gynaecology Research·Mariko KikuchiOsamu Ishihara
Apr 23, 2013·Critical Care : the Official Journal of the Critical Care Forum·Donat R SpahnRolf Rossaint
Jun 29, 2014·British Journal of Anaesthesia·B NascimentoJ H Levy
Aug 13, 2014·Journal of Anesthesia·Yoshinobu KimuraMichiaki Yamakage
Feb 6, 2015·Anesthesiology·Oliver Grottke, Jerrold H Levy

❮ Previous
Next ❯

Citations

Nov 7, 2016·Obstetrics and Gynecology Clinics of North America·Amir A Shamshirsaz, Steven L Clark
Sep 30, 2017·Anesthesia and Analgesia·Marie-Pierre BonnetUNKNOWN French National Experts Committee on Maternal Mortality
Sep 9, 2017·Obstetrics and Gynecology·Daniel W SkupskiGary S Eglinton
Mar 9, 2018·Transfusion·Mark H YazerUNKNOWN Biomedical Excellence for Safer Transfusion (BEST) Collaborative
Jul 12, 2018·Obstetrics and Gynecology·Luis D PachecoGary D V Hankins
Aug 21, 2018·Current Opinion in Hematology·Elizabeth A Godbey, Joseph Schwartz
Mar 22, 2019·Current Pharmaceutical Design·Jaclyn M PhillipsHoma K Ahmadzia
Aug 29, 2019·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Ozhan M TuranKatherine R Goetzinger
Oct 15, 2019·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Sibel OzlerAli Turhan Caglar
Jan 15, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Ali AlhousseiniOffer Erez
Feb 28, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Javier A CarvajalMaría F Escobar
Aug 27, 2019·Critical Care Medicine·Casey A CableDavid J Murphy
Jul 16, 2019·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Francesco ManeschiPalmiero Ianiri
Jan 31, 2020·Yonsei Medical Journal·Jieun KangSeong Jin Choi
Nov 16, 2019·JAMA Network Open·Dacia D C A HenriquezUNKNOWN TeMpOH-1 Research Group
Sep 24, 2020·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Emsal P T YilmazRagıp A Al
Nov 5, 2019·Advances in Anesthesia·Justin E RichardsThomas E Grissom
Jan 23, 2021·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Sibel OzlerAli Turhan Caglar
Nov 17, 2020·Anesthesiology Research and Practice·S Alvarado-RamosJ F Campos-Rodríguez
Sep 15, 2020·American Journal of Obstetrics and Gynecology·Yukako YukiKatsuo Terui
May 15, 2021·American Journal of Perinatology·Bahram SalmanianAlireza A Shamshirsaz

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Perinatology
Luis D PachecoGary D V Hankins
Anesthesia and Analgesia
Anne-Sophie Ducloy-BouthorsEvelyn Lockhart
Blood Transfusion = Trasfusione Del Sangue
Massimo Franchini, Giuseppe Lippi
Philippine Journal of Surgery and Surgical Specialties
J M TANGLAO
Anesthesia and Analgesia
Herbert Schöchl, Christoph J Schlimp
© 2021 Meta ULC. All rights reserved