An Update Review on the Anthelmintic Activity of Bitter Gourd, Momordica charantia

Pharmacognosy Reviews
Sutthaya Poolperm, Wannee Jiraungkoorskul

Abstract

Momordica charantia (Family: Cucurbitales), as known as bitter melon or gourd, is a daily consumption as food and traditional medicinal plant in Southeast Asia and Indo-China. It has been shown to possess anticancer, antidepressant, antidiabetic, anti-inflammatory, antimicrobial, antiobesity, antioxidant, and antiulcer properties. Its common phytochemical components include alkaloids, charantin, flavonoids, glycosides, phenolics, tannins, and terpenoids. This plant is rich in various saponins including momordicin, momordin, momordicoside, karavilagenin, karaviloside, and kuguacin, all of which have been reported to contribute to its remedial properties including antibacterial, antifungal, antiviral, and antiparasitic infections. Based on established literature on the anthelmintic activity of M. charantia and possible mode of action, this review article has attempted to compile M. charantia could be further explored for the development of potential anthelmintic drug.

References

Jan 6, 2010·Evidence-based Complementary and Alternative Medicine : ECAM·A Justin Thenmozhi, P Subramanian
Aug 25, 2010·Cancer Science·Pornsiri PitchakarnTomoyuki Shirai
Aug 26, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Che-Yi ChaoYueh-Hsiung Kuo

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Citations

Jul 26, 2019·BMC Complementary and Alternative Medicine·Muhammad Farooq KhanMohammad A M Wadaan
Jul 23, 2021·Food Chemistry·Chandana SosalagerePoorva Sharma

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Methods Mentioned

BETA
pharmacotherapy

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