Anabolic-androgenic steroids and testosterone precursors: ergogenic aids and sport

Current Sports Medicine Reports
Zoë J Foster, Jeffrey A Housner

Abstract

This article reviews the recent literature on the use of anabolic-androgenic steroids (AAS) for performance enhancement. Recent studies utilizing supraphysiologic doses of testosterone have demonstrated increases in strength and improvements in body composition, despite earlier assertions by the medical community that steroids were ineffective as ergogenic aids. Although data that support the theory of conversion of prohormones, such as androstenediol, to testosterone in the body is available, support for testosterone precursors alone as ergogenic aids is lacking. Drug testing laboratories are utilizing new techniques that analyze carbon-13 levels of urinary steroids to detect exogenously administered steroids as well as the use of urine-manipulating agents. Investigations that seek to refute athletes' various claims for positive drug tests are ongoing. The recent discovery, characterization, and development of a urine test for tetra-hydro-gestrinone, a designer steroid, has brought the issue of performance enhancement once again into the public spotlight. Increasing attention is also being paid to the long-term effects of AAS abuse, as more authors characterize the changes to hematologic, hepatic, lipid, and hormone profiles a...Continue Reading

Citations

Sep 15, 2005·Current Opinion in Pediatrics·Kim D Dorsch, Ali Bell
Feb 20, 2009·Orthopedics·Seth A CheathamDarren L Johnson
Sep 13, 2018·Reproductive Biology and Endocrinology : RB&E·Mahsa DarbandiMohammad Reza Sadeghi
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Aug 12, 2006·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Leonard J Deftos

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