PMID: 589938Dec 1, 1977

Anaemia, iron deficiency and exercise: extended studies in human subjects

Clinical Science and Molecular Medicine
R W CharltonT H Bothwell


1. Ventilation and cardiac frequency were measured during repeated treadmill exercise in three healthy subjects over 36 weeks, before, during and after iron-deficiency anaemia was produced and after iron treatment. The haemoglobin and 2,3-diphosphoglycerate concentrations and the oxygen-binding (P50) were measured. 2. There was an inverse relationship between the haemoglobin concentrations and the 2,3-diphosphoglycerate concentrations and the P50 values. 3. The mean cardiac frequencies during the fourth to tenth minutes of exercise showed a negative correlation with the haemoglobin concentrations in all three subjects, and the mean minute ventilations in two of them.


Nov 1, 1989·Journal of Internal Medicine·P R Dallman
Feb 18, 2015·PloS One·Emily P BrighamElizabeth C Matsui
Oct 1, 1978·British Journal of Haematology·P R DallmanC A Finch
Jan 1, 1992·Nutrition Research Reviews·J D CookB S Skikne
Apr 25, 2007·Critical Reviews in Food Science and Nutrition·Nuzhat HumaMunir A Sheikh
Jan 1, 1979·Vox Sanguinis·P Lundsgaard-Hansen

Related Concepts

Expiratory Airflow
Iron Deficiency Anemia
Diphosphoglyceric Acids
Asiderotic Anemia
Pulse Rate

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