Anaerobic tissue-dissolving abilities of calcium hydroxide and sodium hypochlorite

Journal of Endodontics
S F YangC Stanford

Abstract

Closed root canals likely have an oxygen-free environment; most bacteria in canals are anaerobic. These bacteria and other debris are difficult to remove. Unknown is tissue dissolution with chemicals under these anaerobic conditions. This study evaluated and compared dissolving properties of calcium hydroxide (Ca(OH)2) and sodium hypochlorite (NaOCl) on bovine pulp tissue in aerobic and anaerobic environments. Sixty bovine pulp specimens were dried, then randomly divided into six groups. Groups A and B were immersed in Ca(OH)2 + water solution, whereas group C and D were in 2.5% NaOCl. Groups E and F (controls) specimens were placed in distilled water. Groups A, C, and E were incubated anaerobically, and groups B, D, and F were incubated under regular atmospheric conditions, all for 7 days. Percentages of weight loss were compared between groups. Results showed the following: (a) both chemicals partially dissolved pulp tissue, (b) anaerobic environment did not alter tissue-dissolving properties of Ca(OH)2 or NaOCl, and (c) Ca(OH)2 and NaOCl were equal and more effective than water.

Citations

Sep 8, 2011·Dental Traumatology : Official Publication of International Association for Dental Traumatology·Leif K Bakland, Jens O Andreasen
May 4, 2011·International Endodontic Journal·Z Mohammadi, P M H Dummer
Nov 7, 1999·International Endodontic Journal·L R Fava, W P Saunders
Oct 22, 2008·Journal of Endodontics·Asma A KhanKenneth M Hargreaves
Feb 2, 2018·The Open Dentistry Journal·Zahed MohammadiHamid Jafarzadeh
Dec 10, 2020·Restorative Dentistry & Endodontics·Kimia KhoshrooLobat Tayebi

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