PMID: 3754393Mar 1, 1986Paper

Anaesthesia for Friedreich's ataxia. Case report and review of the literature

Anaesthesia
C F BellR S Jones

Abstract

A patient with Friedreich's ataxia was anaesthetised on two occasions. The neuromuscular blocking agent was atracurium 0.5 mg/kg on the first occasion and tubocurarine 0.5 mg/kg on the second. The effect of each was monitored using the train-of-four twitch technique. Friedreich's ataxia has been reported to cause a marked sensitivity to non-depolarising muscle relaxants and hyperkalaemia, with resulting cardiac dysrhythmias after suxamethonium. This patient did not demonstrate an abnormal response to either relaxant; the operating conditions were satisfactory and recovery was not delayed. These drugs may be safely used in this condition provided that monitoring is adequate.

References

Oct 1, 1984·Anaesthesia·C F BellJ E Utting
Dec 1, 1982·British Journal of Anaesthesia·J M HunterJ E Utting
Oct 1, 1951·Annals of the New York Academy of Sciences·K R UNNA, E W PELIKAN

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Citations

Jan 1, 1989·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·A M Campbell, G A Finley
Apr 16, 1998·Anaesthesia·H MouloudiG Frantzeskos
Jan 1, 1997·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·F N ChuileannainP Misra
Mar 28, 2006·Journal of Clinical Anesthesia·Mihori OikawaKazuo Higa
Apr 30, 2014·Revista española de anestesiología y reanimación·G L Agámez MedinaP J Therrien
Apr 15, 2005·Paediatric Anaesthesia·Carol Pancaro, Dieter Renz
Jan 1, 2014·Orphanet Journal of Rare Diseases·Louise A CorbenUNKNOWN Clinical Management Guidelines Writing Group
Jan 1, 1995·The Journal of International Medical Research·A Abyad, E Kligman

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