Anaesthetic management of phaeochromocytoma

Canadian Anaesthetists' Society Journal
V Pratilas, M G Pratila


The incidence, mortality, physiology, clinical findings and diagnosis of phaeochromocytoma are reviewed. Treatment, after adequate medical stabilization, must be surgical because of the high incidence of malignancy. Alpha-adrenergic receptor blockade and beta-adrenergic receptor blockade in the preoperative period was discussed. Anaesthetic management of patients with phaeochromocytoma requires close monitoring. Virtually all inhalational anaesthetic agents have been used in cases of phaeochromocytoma. Recent reports have favored enflurane. The merits of neuroleptanaesthesia and the various muscle relaxants are also discussed. Most authors favour lidocaine over propranolol for management of dysrhythmias during operation. Phentolamine or sodium nitroprusside are used for hypertension during operation. Hypotension is treated by fluid replacement with nor-epinephrine if a vasopressor becomes necessary. Close monitoring is necessary in the postoperative period. Adequate urinary output is of more importance than actual blood pressure levels.


Jan 1, 1997·Pediatric Surgery International·S H EinJ W Balfe
Nov 1, 1984·Canadian Anaesthetists' Society Journal·M HamajiY Kawashima
Sep 1, 1981·Canadian Anaesthetists' Society Journal·D L Wooster, R I Mitchell
May 1, 1985·Canadian Anaesthetists' Society Journal·D Miller, J A Robblee
Apr 1, 1994·Journal of Cardiothoracic and Vascular Anesthesia·I H LewisV A Jebara
Sep 30, 2000·Paediatric Anaesthesia·H A Hack
Mar 7, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Vlad PopoviciMauro Delorenzi


Jan 1, 1977·Anesthesia and Analgesia·G F JaneczkoR F Albrecht
May 1, 1977·Anesthesiology·K Sumikawa, Y Amakata
May 1, 1977·Canadian Anaesthetists' Society Journal·M El-NaggarE Rosenthal
Sep 1, 1976·Anaesthesia·L Stamenković, J Spierdijk
Nov 1, 1975·Canadian Anaesthetists' Society Journal·G Edelist
Jan 1, 1973·Naunyn-Schmiedeberg's Archives of Pharmacology·M Göthert, C Dreyer
Jan 28, 1967·British Medical Journal·E J RossB J Harries
Jun 1, 1971·British Journal of Anaesthesia·J G Whitwam, W J Russell
Oct 1, 1974·Anesthesiology·C J Kopriva, R Eltringham
Oct 1, 1972·British Journal of Anaesthesia·A D ClarkeP D Challen
May 1, 1974·Annals of Surgery·W H RemineE G Harrison
Aug 1, 1970·Anesthesiology·R L Katz, J T Bigger
Feb 21, 1972·JAMA : the Journal of the American Medical Association·S R Cruz, J A Colwell
Nov 1, 1972·Anesthesiology·L BertolóM Penna
Dec 1, 1969·British Journal of Anaesthesia·M R Salem, A D Ivankovic
Sep 1, 1969·Revista argentina de endocrinología y metabolismo· Barontini de Gutiérrez
Oct 1, 1968·Annals of Surgery·T S HarrisonJ F Seaton
Mar 1, 1961·American Heart Journal·J R CROUTA SJOERDSMA
Apr 1, 1960·American Journal of Surgery·D M HUME
Jan 1, 1962·Anesthesiology·A H GALINDO, T B DAVIS
May 1, 1963·Archives of Surgery·J T PRIESTLEYR W GIFFORD
Aug 1, 1963·Annals of Surgery·G D HUEBNER, P A REED

Related Concepts

Sodium Nitroprusside
Intraoperative Care
Diastolic Blood Pressure
Insufflation Anesthesia
Adrenergic alpha-Antagonists
ADRB2 gene
Anesthesia, Intravenous

Related Feeds

Antiarrhythmic Agents: Mechanisms of Action

Understanding the mechanism of action of antiarrhythmic agents is essential in developing new medications as treatment of cardiac arrhythmias is currently limited by the reduced availability of safe and effective drugs. Discover the latest research on Antiarrhythmic Agents: Mechanism of Action here.


Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

Adrenergic Receptors: Trafficking

Adrenergic receptor trafficking is an active physiological process where adrenergic receptors are relocated from one region of the cell to another or from one type of cell to another. Discover the latest research on adrenergic receptor trafficking here.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.