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Anaesthetised normotensive rats for the detection of hypotensive activity of a beta-adrenoceptor antagonist and other antihypertensive agents
Arzneimittel-Forschung
Jan 1, 1978
De-Jie ChuE Stürmer
PMID: 40564
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Abstract
A simple method for the detection of antihypertensive activity in anaesthetised (66 mg/kg i. v. alpha-chloralose and 20 mg/kg i. v. aprobarbital) normotensive rats is described. Dihydralazine (0.5 to 2 mg/kg i. v.) reduced blood pressure dose-dependently but did not provoke the anticipa...read more
Mentioned in this Paper
Dihydralazine Sulfate
Sembrina
V-Serp
Z-Max
Intra-Arterial Injections
Isoglaucon
Bradycardia
Barbiturates
beta-Chloralose
Antihypertensive Agents
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Anaesthetised normotensive rats for the detection of hypotensive activity of a beta-adrenoceptor antagonist and other antihypertensive agents
Abstract
A simple method for the detection of antihypertensive activity in anaesthetised (66 mg/kg i. v. alpha-chloralose and 20 mg/kg i. v. aprobarbital) normotensive rats is described. Dihydralazine (0.5 to 2 mg/kg i. v.) reduced blood pressure dose-dependently but did not provoke the anticipa...read more
Mentioned in this Paper
Dihydralazine Sulfate
Sembrina
V-Serp
Z-Max
Intra-Arterial Injections
Related Papers
Paper Details
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