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Anaesthetised normotensive rats for the detection of hypotensive activity of a beta-adrenoceptor antagonist and other antihypertensive agents

Arzneimittel-Forschung

Jan 1, 1978

De-Jie ChuE Stürmer

PMID: 40564

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Abstract

A simple method for the detection of antihypertensive activity in anaesthetised (66 mg/kg i. v. alpha-chloralose and 20 mg/kg i. v. aprobarbital) normotensive rats is described. Dihydralazine (0.5 to 2 mg/kg i. v.) reduced blood pressure dose-dependently but did not provoke the anticipa...read more

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Dihydralazine Sulfate
Sembrina
V-Serp
Z-Max
Intra-Arterial Injections
Isoglaucon
Bradycardia
Barbiturates
beta-Chloralose
Antihypertensive Agents
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Anaesthetised normotensive rats for the detection of hypotensive activity of a beta-adrenoceptor antagonist and other antihypertensive agents

Arzneimittel-Forschung

Jan 1, 1978

De-Jie ChuE Stürmer

PMID: 40564

DOI:

Abstract

A simple method for the detection of antihypertensive activity in anaesthetised (66 mg/kg i. v. alpha-chloralose and 20 mg/kg i. v. aprobarbital) normotensive rats is described. Dihydralazine (0.5 to 2 mg/kg i. v.) reduced blood pressure dose-dependently but did not provoke the anticipa...read more

Mentioned in this Paper

Dihydralazine Sulfate
Sembrina
V-Serp
Z-Max
Intra-Arterial Injections

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