Anagen Effluvium after Methotrexate: An Idiosyncratic Reaction

International Journal of Trichology
Preema SinhaAnwita Sinha

Abstract

Low-dose methotrexate (MTX) is the backbone of treatment for extensive psoriasis vulgaris not responding to topical therapy. Since its induction for the treatment of psoriasis in the 1970, its short- and long-term side effect profile has been extensively studied. Hair loss with MTX has been reported mostly with high-dose MTX used in chemotherapy. Here, we report a case of guttate psoriasis who presented with acute-onset anagen effluvium following the administration of only two doses of MTX 7.5 mg per week.

References

Feb 1, 1989·Journal of the American Academy of Dermatology·V H Price, C L Gummer
Mar 27, 2002·The Pharmacogenomics Journal·S T PullarkatH J Lenz
Jan 5, 2011·International Journal of Rheumatic Diseases·Anand N MalaviyaSujata Sawhney
Aug 27, 2013·Indian Journal of Dermatology, Venereology and Leprology·Amrinder J Kanwar, Tarun Narang

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