Analgesic effects of intra-articular morphine during and after knee arthroscopy: a comparison of two methods

Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association
O LundinJ Karlsson

Abstract

The objective of this study was to compare the analgesic effects of intra-articularly administered bupivacaine with bupivacaine/morphine during and after therapeutic knee arthroscopy. In a prospective, randomized study, 50 patients with clinical signs of medial meniscal injury were allocated to two groups, A and B. The patients in group A received 40 mL of 0.25% bupivacaine while the same dose of bupivacaine combined with 1 mg of morphine sulphate was administered in group B. Pain was estimated using the visual analogue scale (VAS) during surgery and at 2, 4, 6, and 24 hours after the operation was completed. Supplementary analgesic requirements were also registered, as well as the patients' overall rating of the entire procedure. The pain scores were significantly lower in Group B throughout the whole postoperative observation period. However, no significant differences were found between the two groups in terms of intraoperative pain scores, supplementary analgesic requirements, or the overall rating of the procedure. This study provides evidence that arthroscopic surgery can be performed in a safe manner after intra-articularly administered bupivacaine with or without low-dose morphine. The combination of low-dose morphine a...Continue Reading

Citations

Aug 30, 2008·Der Orthopäde·C J P Simanski
Jan 13, 2005·Archives of Orthopaedic and Trauma Surgery·Hanife AltunkayaAhmet Bayar
Mar 10, 2005·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Ryan C GoodwinRichard D Parker
Jul 28, 2007·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·John R ZunigaMark Kozacko
Sep 9, 2005·Acta Anaesthesiologica Scandinavica·B TuncerM Arslan
Aug 13, 2015·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Ye YangGuang-Hua Lei
Sep 14, 2017·The American Journal of Sports Medicine·Geoffrey D AbramsJason L Dragoo
Dec 29, 2000·The Journal of Bone and Joint Surgery. American Volume·S S Reuben, J Sklar

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