PMID: 8952239Nov 1, 1996Paper

Analgesic efficacy and safety of an intraoral lidocaine patch

The Journal of the American Dental Association
E V HershL M Levin

Abstract

The effectiveness of intraoral II-docaine patches was tested by asking participants to rate the pain experienced after insertions of a 25-gauge needle. Needlesticks were performed at baseline and at various time points after patch placement. Each needlestick included contact with the periosteum. Lidocaine patches achieved significantly better analgesia than the placebo within 2.5 to five minutes after placement. Drug-related side effects were minimal and venous blood levels of lidocaine were low, averaging 10 to 14 times less than those achieved with a typical injection of lidocaine plus epinephrine. The authors conclude that the lidocaine patches used in this study are effective and safe in reducing needle insertion pain in adults.

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Citations

Jul 25, 2009·European Archives of Paediatric Dentistry : Official Journal of the European Academy of Paediatric Dentistry·J G Meechan
Apr 23, 2002·International Journal of Paediatric Dentistry·D Ram, B Peretz
Feb 10, 2000·Journal of Dentistry·J G Meechan
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Feb 11, 2014·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Yuriko NikiHirotsugu Okamoto
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Aug 25, 2016·Expert Opinion on Drug Delivery·Michelle Franz-MontanEneida de Paula

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