PMID: 11913823Mar 27, 2002Paper

Analgesic, sedative and haemodynamic effects of spinally administered romifidine in female goats

Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine
AmarpalK Pratap

Abstract

The present study was designed to evaluate the analgesic, sedative and haemodynamic effects of spinally administered romifidine in goats. Ten female healthy goats weighing 14-18 kg were randomly divided into two groups, I and II, of five animals each. Romifidine was administered spinally at rates of 50 and 75 microg/kg body weight in the animals of groups I and II, respectively, into the lumbosacral space. The treatments were compared based on their effects on analgesia, sedation, ataxia, heart rate, respiratory rate, rectal temperature, mean arterial pressure, central venous pressure, electrocardiogram and haemato-biochemical parameters. The objective parameters were analysed statistically using paired t-test and Duncan's multiple range test. Depth of analgesia was measured by recording the response to pin prick at different regions and was graded on a scale from 0 to 3. Moderate to complete analgesia was recorded at perineum and flank in both groups. Sedation was moderate in both groups. Ataxia was observed in all the animals but it was more pronounced in group II. Heart rate decreased significantly (P < 0.01) in both groups. A decrease in respiration rate was also recorded in both groups but it was more significant (P < 0.01...Continue Reading

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Citations

Jan 21, 2016·The Veterinary Record·M A Marzok, S A El-Khodery
Jun 23, 2009·Veterinary Anaesthesia and Analgesia·Mohamed Marzok, Sabry El-Khodery
Jan 6, 2009·Veterinary Anaesthesia and Analgesia·Virendra SinghHari P Aithal
Aug 28, 2007·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·H MeyerJ Rehage
Mar 17, 2010·Veterinary Anaesthesia and Analgesia·Véronique Martin-BouyerIngeborgh Polis

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