Analogies and disparities among scintigraphic bone tracers in the diagnosis of cardiac and non-cardiac ATTR amyloidosis

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
Claudio RapezziAgnese Milandri

Abstract

In this issue of JNC, BW Spery and Coll report a retrospective analysis of 57 patients with transthyretin-related amyloidosis (ATTR) in an advanced phase of the disease who underwent 99mTechnetium-pyrophosphate (99mTcPYP) scintigraphy. Although relatively small and "negative," the study is relevant since it broadens our knowledge on the uptake of "bone tracers" in ATTR and contributes to understand the limitations of the clinical use of scintigraphy in this disease. The paper raises, directly or indirectly, at least three questions: To what extent are the different bone tracers interchangeable for the diagnosis of ATTR cardiac amyloidosis? Are bone tracers able to image non-cardiac ATTR amyloidosis? What is the explanation for the variable performance of the different bone tracers in the diagnosis of cardiac and extracardiac ATTR amyloidosis?

References

May 11, 2002·European Journal of Nuclear Medicine and Molecular Imaging·Max PuilleRichard Bauer
Sep 20, 2005·Journal of the American College of Cardiology·Enrica PeruginiClaudio Rapezzi
Nov 12, 2010·European Journal of Nuclear Medicine and Molecular Imaging·Claudio RapezziAngelo Branzi
Apr 3, 2012·Revista Española De Cardiología·F Javier de Haro-del MoralJavier Segovia-Cubero
Jul 11, 2012·Annals of Nuclear Medicine·Yasushi YamamotoKazuaki Tanabe
Jul 14, 2012·JACC. Cardiovascular Imaging·Candida Cristina QuartaClaudio Rapezzi
Jan 25, 2014·Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis·Andor W J M GlaudemansBouke P C Hazenberg
Jun 19, 2014·European Heart Journal Cardiovascular Imaging·David F HuttAshutosh D Wechalekar
Sep 26, 2015·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Axel Van Der GuchtThibaud Damy
Oct 16, 2015·Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis·Arnault GalatThibaud Damy
Nov 26, 2015·International Journal of Cardiology·Suzane Garcia FerreiraClaudio Tinoco Mesquita
Feb 6, 2016·Upsala Journal of Medical Sciences·Björn PilebroTorbjörn Sundström
May 5, 2016·Circulation·Julian D GillmorePhilip N Hawkins
Jul 18, 2016·JACC. Cardiovascular Imaging·Arnault GalatJean Rosso
Jul 30, 2016·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Miriam A Stats, James R Stone
Nov 3, 2016·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Mukedaisi AbuliziEmmanuel Itti
Apr 28, 2017·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Axel Van Der GuchtEmmanuel Itti
May 26, 2017·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Francesco CappelliFederico Perfetto
Dec 1, 2017·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Ji Can YangAnthony F Yu
Jan 19, 2018·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Brett W SperryWael A Jaber

❮ Previous
Next ❯

Citations

Mar 1, 2019·Current Cardiology Reports·Matthieu Pelletier-GalarneauFrancois Harel
May 16, 2020·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Fadi G Hage, Wael A AlJaroudi
Feb 12, 2020·Nature Reviews. Cardiology·Ana Martinez-NaharroMarianna Fontana
Jul 21, 2020·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Kshama Wechalekar, Ashutosh D Wechalekar
Feb 16, 2019·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Chiara GalliniFrancesco Cappelli
Mar 6, 2019·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Patrick MartineauMatthieu Pelletier-Galarneau
Apr 13, 2019·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Gary R Small, Terrence D Ruddy
Nov 7, 2019·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Stuart C Ramsay, Claire Cuscaden
Nov 5, 2020·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Li Xin ZhangMatthieu Pelletier-Galarneau
Aug 4, 2019·European Journal of Internal Medicine·Antonis S ManolisHelen Melita
Dec 23, 2019·JACC. Cardiovascular Imaging·Maria Beatrice MusumeciClaudio Rapezzi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Amyloidosis

Cardiac amyloidosis is a myocardial disease characterized by extracellular amyloid infiltration throughout the heart. Discover the latest research on cardiac amyloidosis here.

Related Papers

Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis
Yukio Ando
JACC. Cardiovascular Imaging
Jason N DunguLisa J Anderson
© 2022 Meta ULC. All rights reserved