PMID: 18421879Apr 22, 2008Paper

Analysis and evaluation of S-phenylmercapturic acid as a biomarker for benzene exposure

Wei sheng yan jiu = Journal of hygiene research
Qiao LuoShi-Zhen Song

Abstract

Since urinary S-phenylmercapturic acid concentration could be well related to benzene exposure, it could be a sensitive and specific biomarker of low-level benzene exposure. SPMA may be determined by HPLC, LC/MS, GC/MS and ELISA methods. The abroad methods of determination of urinary SPMA were reviewed in detail in recently years and the validation and application of urinary SPMA as a biomarker for occupation benzene exposure were evaluated.

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