Analysis of a Systematic Review About Blue Light-Filtering Intraocular Lenses for Retinal Protection: Understanding the Limitations of the Evidence

JAMA Ophthalmology
Laura E DownieTianjing Li

Abstract

Cataract surgery, with intraocular lens (IOL) implantation, is the most common ocular surgical procedure worldwide. It has been suggested that IOLs that selectively attenuate short wavelength visible light (blue light-filtering IOLs) may be beneficial for macular health. Whether blue light-filtering IOLs impart retinal photoprotection is of public health relevance, particularly in the context of aging demographics and the increasing global prevalence of age-related macular degeneration. This review analyzes and interprets the key findings, including consideration of the implications for practice and future research, of a 2018 Cochrane systematic review that evaluated the efficacy and safety of blue light-filtering IOLs for providing protection to macular health and function. The Cochrane systematic review included 51 randomized controlled trials that were performed in 17 countries. The trials involved adults undergoing cataract surgery in which a blue light-filtering IOL was compared with an equivalent non-blue light-filtering IOL. Study follow-up periods ranged from 1 month to 5 years. Together, these studies considered clinical outcomes in more than 5000 eyes. There was limited ability to combine data across trials (to draw o...Continue Reading

References

Jul 7, 2001·Free Radical Biology & Medicine·S DaviesM E Boulton
Apr 20, 2004·Journal of Cataract and Refractive Surgery·Janet R SparrowJilin Zhou
Sep 10, 2004·JAMA : the Journal of the American Medical Association·Catherine D DeAngelisUNKNOWN International Committee of Medical Journal Editors
Feb 1, 2006·Acta Ophthalmologica Scandinavica·Marja-Liisa Vuori, Maija Mäntyjärvi
Aug 11, 2009·Journal of Refractive Surgery·Aldo CaporossiLeonardo Ciompi
Jan 22, 2013·Ophthalmology·Frederick L FerrisUNKNOWN Beckman Initiative for Macular Research Classification Committee
Jan 30, 2013·BMJ : British Medical Journal·Nick Black
Jan 15, 2014·Lancet·Paul GlasziouElizabeth Wager
Dec 2, 2014·American Journal of Ophthalmology·Thomas J Liesegang, George B Bartley
Mar 18, 2015·Nature Reviews. Cardiology·Stefan JamesChristopher B Granger
Jan 25, 2017·Investigative Ophthalmology & Visual Science·Jonathan B LinRajendra S Apte
Mar 9, 2017·The British Journal of Ophthalmology·Andrew LawTianjing Li
Jul 7, 2017·Trials·Paula R WilliamsonBridget Young
Oct 19, 2017·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Laura E Downie
Oct 19, 2017·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·John G LawrensonLaura E Downie

❮ Previous
Next ❯

Citations

Apr 9, 2019·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Sumeer SinghLaura E Downie
Oct 11, 2019·Clinical & Experimental Ophthalmology·Sumeer SinghLaura E Downie
Oct 2, 2020·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Beatriz RedondoRaimundo Jiménez
May 15, 2019·International Journal of Molecular Sciences·Chao-Wen LinChang-Hao Yang
Jan 21, 2021·Expert Opinion on Investigational Drugs·Massimo NicolòCarlo Enrico Traverso
Mar 19, 2021·Seminars in Ophthalmology·Aldo VaggeCarlo E Traverso
Mar 1, 2021·Journal of the American Academy of Dermatology·Amaris N GeislerHenry W Lim
Jul 3, 2021·Medicina·Ivajlo PopovVladimir Krasnik
Aug 8, 2021·Journal of Clinical Medicine·Emiliano Di Carlo, Albert J Augustin
Oct 6, 2021·Eye & Contact Lens·María Carmen Sánchez-GonzálezMaría-José Bautista-Llamas

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Aging

This feed focuses on cellular aging with emphasis on mitochondria, autophagy, and metabolic processes associated with aging and longevity. Here is the latest research on cell aging.

Cell Aging (Keystone)

This feed focuses on cellular aging with emphasis on the mitochondria, autophagy, and metabolic processes associated with aging and longevity. Here is the latest research on cell aging.

Related Papers

Klinische Monatsblätter für Augenheilkunde
Albert J Augustin
Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
James A DavisonOrkun Muftuoglu
© 2022 Meta ULC. All rights reserved