Analysis of a theoretical model based on similarity for studying RNA base pairings

Journal of Theoretical Biology
P Di GennaroM Termini

Abstract

A theoretical model for studying RNA base pairing is presented, based on similarity measures of the bases and corresponding indexes. Similarity calculations are made by evaluating atomic importance in molecules, a method that uses an original method for the calculation of electronic energy. The application of the model to both Watson-Crick and non-Watson-Crick pairings is commented on. Some theoretical considerations concerning the capability of the genetic code to repair dangerous mutations contribute to the ongoing debate.

Citations

Aug 27, 2005·Journal of Theoretical Biology·Yue-Lan WangJie Yang

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