Analysis of Appendiceal Neoplasms on 3544 Appendectomy Specimens for Acute Appendicitis: Retrospective Cohort Study of a Single Institution

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Enver KunduzSebahattin Destek

Abstract

BACKGROUND Appendiceal neoplasms are rare and generally determined in appendectomy specimens for acute appendicitis. Depending on a tumor's histopathology and size, appendectomy or right hemicolectomy are the surgical treatment options. Adenocarcinomas, mucinous neoplasms, goblet cell carcinoids and neuroendocrine tumors are the types of the primary appendiceal neoplasm histopathology. In this study, we aimed to determine the incidence of appendiceal neoplasms in an acute appendicitis cohort. Also, histopathological distributions, demographic data, preoperative radiological diagnosis, and intraoperative findings were revealed for analysis, retrospectively. MATERIAL AND METHODS Between October 2011 and September 2017, 3554 appendectomies were performed for acute appendicitis in Bezmialem University Hospital, Istanbul Turkey. The medical records of these consecutive 3554 patients were evaluated retrospectively. After the histopathological analysis of the appendectomy specimens, a total of 28 patients were detected as having appendiceal neoplasm including appendiceal adenocarcinoma, low grade mucinous neoplasia, and appendiceal neuroendocrine tumors. RESULTS Appendiceal neoplasms were determined in 28 out of 3554 acute appendiciti...Continue Reading

Citations

Apr 6, 2019·Journal of Surgical Case Reports·Catarina MoraisVítor Valente
Sep 11, 2020·Case Reports in Pathology·Numbereye NumbereAaron R Huber
Nov 11, 2020·Journal of Surgical Oncology·Adrienne B ShannonGiorgos C Karakousis
Jul 8, 2021·Journal of Pathology and Translational Medicine·Dong-Wook KangUNKNOWN Gastrointestinal Pathology Study Group of the Korean Society of Pathologists

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