Analysis of Biomolecules Based on the Surface Enhanced Raman Spectroscopy

Nanomaterials
Min JiaHongyan Zhang

Abstract

Analyzing biomolecules is essential for disease diagnostics, food safety inspection, environmental monitoring and pharmaceutical development. Surface-enhanced Raman spectroscopy (SERS) is a powerful tool for detecting biomolecules due to its high sensitivity, rapidness and specificity in identifying molecular structures. This review focuses on the SERS analysis of biomolecules originated from humans, animals, plants and microorganisms, combined with nanomaterials as SERS substrates and nanotags. Recent advances in SERS detection of target molecules were summarized with different detection strategies including label-free and label-mediated types. This comprehensive and critical summary of SERS analysis of biomolecules might help researchers from different scientific backgrounds spark new ideas and proposals.

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Citations

Dec 25, 2019·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Chunxia LiYuling Wang
Oct 28, 2020·ACS Applied Materials & Interfaces·Lena GolubewaPolina Kuzhir
Oct 27, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Sravani Kaja, Amit Nag
Jan 15, 2022·Optics Letters·Wang Tiankun, Ng Shashiong

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Methods Mentioned

BETA
surface enhanced Raman spectroscopy
biosensors
sandwich immunoassay
chip
biosensor
fluorescence
PCR
PCA
sandwich
chips

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