Analysis of Choroidal Thickness in Children with Congenital Aniridia.

Current Eye Research
Hui ChenHaotian Lin

Abstract

Purpose: To evaluate the choroidal thickness (CT) in children with congenital aniridia in comparison with age-matched controls. Methods: This was a cross-sectional, observational study that included 64 eyes of 32 children with congenital aniridia (aged 5-12 years) and 80 eyes of 40 healthy subjects who were age-matched. In all subjects, subfoveal choroidal thickness (SFCT) was assessed at 750-μm intervals from the fovea to 1.5 mm in the temporal and nasal directions with spectral-domain optical coherence tomography (SD-OCT). Results: The mean SFCT was 207.67 ± 30.99 µm in the aniridic eyes. This SFCT was significantly thinner than that in control eyes (288.55 ± 30.06 µm) (P < .001). The SFCTs at 1.5 mm and 0.75 mm intervals in the temporal and nasal directions from the fovea were also significantly thinner in eyes with aniridia than control eyes (P < .001).There was a significant negative correlation between the SFCT and axial length in eyes with aniridia (B = -10.60, 95%CI = -19.31~-1.89, P = .017). Conclusions: The subfoveal and parafoveal CTs were significantly thinner in eyes with congenital aniridia than in control eyes. These choroidal changes could open up a new way for the research related to the pathophysiology of cong...Continue Reading

References

Jul 27, 2001·Progress in Retinal and Eye Research·S S Hayreh
May 23, 2008·Acta Ophthalmologica·Ulla EdénKristina Tornqvist
Jul 22, 2008·American Journal of Ophthalmology·Richard F SpaideMaria C Pozonni
Oct 22, 2008·Acta Ophthalmologica·Helena LeeMichael O'Keefe
Jun 6, 2009·Acta Ophthalmologica·Gerd HolmströmEva Larsson
Jul 1, 2009·Developmental Biology·Noa DavisRuth Ashery-Padan
Jan 16, 2010·Eye·G A LuttyD S McLeod
Dec 20, 2012·Investigative Ophthalmology & Visual Science·José M Ruiz-MorenoMasahiro Akiba
Nov 5, 2013·The British Journal of Ophthalmology·Tomo NishiNahoko Ogata
Dec 29, 2013·Journal of Pediatric Ophthalmology and Strabismus·Bhupesh SinghVirender S Sangwan
Jun 10, 2017·Current Opinion in Ophthalmology·Hyun Taek LimHyuna Kim

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Ophthalmology
CADENAS UGIDOS
Indian Journal of Ophthalmology
N SenI S Jain
Vojenské zdravotnické listy
R KRIZ
American Journal of Human Genetics
M W SHAWJ V Neel
Transactions of the American Ophthalmological Society
C C Rush
© 2021 Meta ULC. All rights reserved