Analysis of clinical features of RPE adenoma.

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Nan ZhouWenbin Wei

Abstract

This study aims to evaluate the clinical features of adenoma of the retinal pigment epithelium (RPE) and eye-sparing treatment for it. The patients underwent measurement of visual acuity and intraocular pressure, slit-lamp examination, ophthalmoscopy, fluorescein fundus angiography (FFA), indocyanine green angiography (ICGA), color Doppler imaging (CDI), and magnetic resonance imaging (MRI). The tumors were endoresected and studied histopathologically. Of the 16 Asian patients, 15 had RPE adenoma and 1 had RPE adenocarcinoma. Visual acuity decreased in three cases, mainly due to the macular detachment. All tumors were solitary and unilateral and measured from 1.7 × 3.2 × 2.4 to 9.3 × 8.0 × 6.6 mm3. The tumor was located in the macular area in 2 patients, in the juxtapapillary area in 1 patient, and in the peripheral fundus in 13 patients. The tumors were yellow-pink in 3 patients and brown in 13 patients. The tumors showed hypofluorescence in early stage and mottled hyperfluorescence with prominent leakage in late stage on fluorescein angiography. CDI demonstrated arterial blood signals within tumor, and MRI demonstrated hyperintensity and hypointensity in the T1- and T2-weighted images, respectively. The tumors were positive f...Continue Reading

References

Dec 1, 1978·Archives of Ophthalmology·D Minckler, A W Allen
Nov 11, 1992·Ophthalmology·J A ShieldsP De Potter
Jun 1, 1991·Ophthalmology·J A ShieldsV Sivalingam
Jul 1, 1987·The British Journal of Ophthalmology·S RamahefasoloG Coscas
Jan 1, 1971·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·A B de Haan
Apr 1, 1972·American Journal of Ophthalmology·R L FontB S Fine
Nov 1, 1970·The British Journal of Ophthalmology·A Garner
Jan 1, 1981·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·H Laqua
Feb 1, 1995·American Journal of Ophthalmology·J T FanR J Campbell
Aug 1, 1996·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·P T FingerJ B Walsh
May 2, 1998·Archives of Ophthalmology·C EdelsteinR C Eagle
Apr 25, 2001·Archives of Ophthalmology·J A ShieldsA D Singh
Apr 1, 1958·American Journal of Ophthalmology·J R FAIR
Apr 1, 1958·American Journal of Ophthalmology·G D THEOBALDH Q KIRK
Mar 1, 1965·Archives of Ophthalmology·F C BLODIE T SORNSON
Jun 29, 2005·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Nikolaos TrichopoulosSusan Schneider
Sep 12, 2009·Ophthalmology·Jerry A ShieldsSara E Lally
Apr 10, 2010·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Wenbin WeiBin Li

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