Analysis of clinical, radiological and laboratory variables in psoriatic arthritis with 25 Japanese patients

The Journal of Dermatology
Hideki MaejimaKensei Katsuoka

Abstract

Psoriatic arthritis (PsA) has many clinical and radiological manifestations but lacks a specific laboratory marker. The aim of the present study was to identify noteworthy features in PsA patients on routine clinical examinations. The subjects were 25 PsA patients who were classified based on the Classification of Psoriatic Arthritis (CASPAR) criteria. The clinical and radiological findings and laboratory parameters were analyzed by retrospective chart review. On clinical examination, dactylitis was present in 13 (52%) of 25 patients, swollen and/or tender Achilles tendons were present in nine (36%), and sacroiliitis was present in eight (32%). Of the radiological features, juxta-articular new bone formation (JANF) was seen in 12 (48%), extra-articular new bone formation was seen in nine (36%) and sacroiliitis was seen in six (24%). Dactylitis and JANF had the highest prevalence rates. The Psoriasis Area and Severity Index score, swollen and/or tender joint count, erythrocyte sedimentation rate, C-reactive protein, and matrix metalloproteinase-3 were higher in patients with sacroiliitis than in those without sacroiliitis (P < 0.05). Dactylitis, JANF and sacroiliitis may be noteworthy manifestations in Japanese patients with PsA.

References

Aug 1, 1991·British Journal of Rheumatology·J C Torre AlonsoC Lopez Larrea
Jan 1, 1973·Seminars in Arthritis and Rheumatism·J M Moll, V Wright
Sep 3, 1998·Seminars in Arthritis and Rheumatism·B M RothschildM Eaton
Jul 15, 2006·Annals of the Rheumatic Diseases·P S HelliwellUNKNOWN CASPAR Study Group
Jul 28, 2006·Arthritis and Rheumatism·William TaylorUNKNOWN CASPAR Study Group
Dec 1, 2007·Arthritis and Rheumatism·Vinod ChandranDafna D Gladman

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Citations

Mar 20, 2016·The Journal of Dermatology·Toshiyuki YamamotoUNKNOWN Working Group of the Epidemiological Survey in the Japanese Society for Psoriasis Research
Jul 6, 2014·Journal of the European Academy of Dermatology and Venereology : JEADV·A P VillaniD Jullien
Dec 12, 2017·The Journal of Dermatology·Toshiyuki Yamamoto, Akira Kawada
Jun 4, 2011·Current Opinion in Rheumatology

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