Analysis of clinical utilization of ring applicator for combined intracavitary/interstitial image-guided brachytherapy treatment in Chinese patients with locally advanced cervical cancer

Journal of Contemporary Brachytherapy
Zhipeng ZhaoGuanghui Cheng

Abstract

To analyze the results of clinical utilization of ring applicator for combined intracavitary (IC)/interstitial (IS) image-guided brachytherapy (BT) technique in locally advanced cervical cancer (LACC), and to explore the application conditions of IC/IS BT approach with this applicator for Chinese patients. IC/IS BT was performed in total of 95 LACC patients, who already received external beam radiotherapy. In forty-three of these patients, utilization of ring applicator in brachytherapy was done, including IC/IS BT approach with ring applicator for 65 fractions. Clinically optimized IC/IS BT plan with ring applicator (IC/IS treatment) and additionally generated optimized plan without needle use (IC research) were designed, respectively. Dosage differences in target regions and organs at risk (OARs) were analyzed between both the plans. Four planes were selected in the longitudinal direction of uterine cervix and divided the 360° area around the tandem into eight equal sectors. Tumor target features and prescription dose distributions on different planes were described. The usage rate of ring applicator with most suitable ring diameter of 26 mm was 45.3% in Chinese cervical cancer patients. The high-risk clinical target volume (...Continue Reading

Methods Mentioned

BETA
IGBT

Software Mentioned

SPSS
RetroEMBRACE

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