Analysis of coronary flow fields in thoracotomized dogs.

Circulation Research
H B AtabekD J Patel

Abstract

A nonlinear theory of pulsatile flow was used to investigate the detailed flow field in the left circumflex coronary artery of anesthetized open-chest dogs. Studies were carried out under a wide range of blood pressures and flow rates induced by intravenous infusions of dipyridamole. The results indicated that (1) the flow profiles, although less blunt than those in the descending aorta, are still nonparabolic, (2) the wall shear in the coronary arteries maintains a high value through diastole, and (3) during intravenous infusions of dipyridamole both coronary flow and wall shear increase. The peak value of the shear stress during these infusions, which reached 360 dynes/cm2, can approach the yield stress value of 400 dynes/cm2 reported by Fry for endothelial cells.

References

Jan 1, 1974·Annual Review of Physiology·D J PatelP A Kot

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Citations

Jan 7, 2010·Medical & Biological Engineering & Computing·William Tsai, Omer Savaş
Jul 1, 1995·The American Journal of Cardiology·G N LevineG J Balady
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May 15, 2015·Physics in Medicine and Biology·Lili NiuHairong Zheng

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