PMID: 2499550Jan 1, 1989Paper

Analysis of differing patterns of cross-reactivity of honeybee and yellow jacket venom-specific IgE: use of purified venom fractions

International Archives of Allergy and Applied Immunology
J I WypychR E Reisman

Abstract

Prior studies of sera from insect sting-allergic patients have analyzed the relationship of coexisting honeybee venom- and yellow jacket venom-specific IgE. Radioallergosorbent (RAST)-inhibition tests with these venoms revealed four different patterns of activity. In this present study, purified fractions prepared from these venoms were used to analyze these varying patterns. The hyaluronidases of yellow jacket venom and honeybee venom showed extensive cross-reaction. The phospholipases from these venoms showed minimal cross-reactivity; antigen 5 was restricted to yellow jacket venom. There was a high molecular weight component in yellow jacket venom with immunologic properties similar to honeybee venom acid phosphatase. Sera from individual patients showed quantitative and qualitative differences in the reactions to the major components of both venoms. The differences in the RAST-inhibition patterns in patients with elevated levels of both honeybee venom- and yellow jacket venom-specific IgE are accounted for by these differences as well as by differences in the cross-reactivity between the individual components.

Citations

Dec 18, 2009·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Mitja Kosnik, Peter Korosec
Jun 30, 2009·Wiener klinische Wochenschrift·Renato ErzenMitja Kosnik
Aug 19, 2011·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M T KrishnaUNKNOWN British Society for Allergy and Clinical Immunology
Mar 10, 2004·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·W HemmerR Jarisch
Oct 4, 2005·Allergy·B M BilóUNKNOWN EAACI Interest Group on Insect Venom Hypersensitivity
Feb 1, 1992·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S JeepG Kunkel
Sep 23, 2014·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·W Hemmer
Nov 23, 2019·Current Protein & Peptide Science·Le CuiKai Guan
Nov 17, 2009·The Journal of Allergy and Clinical Immunology·Chunsheng JinWolfgang Hemmer

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