Analysis of enhancement pattern of flat gallbladder wall thickening on MDCT to differentiate gallbladder cancer from cholecystitis

AJR. American Journal of Roentgenology
Soo Jin KimJin Young Choi

Abstract

The objective of our study was to determine the diagnostic value of analyzing the pattern of gallbladder wall enhancement on MDCT to characterize diffuse gallbladder wall thickening as benign or malignant. MDCT scans obtained during the portal venous phase in 78 patients with gallbladder wall thickening caused by various pathologic conditions were retrospectively reviewed by two blinded observers. The CT features of benign and malignant gallbladder wall thickening were compared by means of univariate and multivariate analyses. The study cases were then divided into five patterns according to enhancement pattern. Using these five patterns, two radiologists reviewed the MDCT images and recorded their diagnostic confidence for differentiating benign versus malignant cause on a 5-point scale. The diagnostic performance of CT was evaluated by each observer using a receiver operating characteristic curve analysis. The thicknesses of the inner and outer layers ("thick" enhancing inner layer > or = 2.6 mm, "thin" outer layer < or = 3.4 mm), strong enhancement of the inner wall, and irregular contour of the affected wall were significant predictors for a malignant cause of gallbladder wall thickening (p < 0.001). The two-layer pattern w...Continue Reading

References

Nov 1, 1992·Annals of Surgery·Y ShiraiH Watanabe
May 1, 1991·World Journal of Surgery·Y OguraM Tabata
May 1, 1991·AJR. American Journal of Roentgenology·S A TeefeyS A Bigler
Feb 1, 1990·Archives of Surgery·J H DonohueM A Adson
Mar 1, 1985·Journal of Surgical Oncology·H U SonsB S Joel
Apr 1, 1984·AJR. American Journal of Roentgenology·S N WeinerJ Hoffman
Aug 1, 1984·AJR. American Journal of Roentgenology·R L SmathersJ P Heiken
Feb 1, 1981·AJR. American Journal of Roentgenology·W J ShlaerF W Scheible
May 1, 1996·AJR. American Journal of Roentgenology·J FidlerL Layfield
Mar 28, 1998·Abdominal Imaging·J I HwangP R Mueller
Jul 3, 1999·World Journal of Surgery·H OnoyamaY Saitoh
Mar 22, 2001·Radiographics : a Review Publication of the Radiological Society of North America, Inc·A D LevyC A Rohrmann
Mar 8, 2002·Annals of Surgery·Sharon M WeberWilliam R Jarnagin
Mar 19, 2003·The British Journal of Radiology·R ZissinG Gayer
Jun 23, 2004·AJR. American Journal of Roentgenology·David GrandElliott Fishman
Jan 24, 2007·AJR. American Journal of Roentgenology·Adriaan C van Breda VriesmanJulien B C M Puylaert
Jun 21, 2007·AJR. American Journal of Roentgenology·Brian H ChingFergus V Coakley

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Citations

May 15, 2012·Abdominal Imaging·Swati D DeshmukhElliot K Fishman
Nov 12, 2013·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Keita KaiOsamu Tokunaga
Dec 5, 2009·World Journal of Gastroenterology : WJG·Tze-Yu LeeShyr-Ming Sheen-Chen
Jun 8, 2014·Digestive Diseases and Sciences·Gareth Morris-Stiff, Shahid Farid
Nov 26, 2015·Clinical Radiology·S W KimK Y Won
Dec 1, 2012·Journal of the American College of Surgeons·Charles Henry Caldow PilgrimT Clark Gamblin
Feb 24, 2016·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Abdulrahman Y HammadT Clark Gamblin
May 19, 2010·Gastroenterology Clinics of North America·Richard M GoreJonathan W Berlin
Jan 3, 2013·Journal of Magnetic Resonance Imaging : JMRI·Soo Jin KimByung Ihn Choi
Jan 1, 2013·ISRN Radiology·Abhishek VijayakumarB S Shivaswamy
Mar 13, 2015·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Vincent M MellnickKhaled M Elsayes
Mar 15, 2014·Journal of Computer Assisted Tomography·Charles H MitchellSiva P Raman
Apr 10, 2014·American Journal of Clinical Pathology·Iván RoaXabier de Aretxabala
Oct 31, 2019·Clinical and Translational Gastroenterology·Mingyu ChenUNKNOWN Written on behalf of the AME Gallbladder Cancer Collaborative Group
May 16, 2020·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Susan JohnMatthew D F McInnes
Jun 1, 2018·Gastroenterology Research and Practice·Hiroshi ItsukiKazuaki Chayama
Feb 20, 2020·Japanese Journal of Radiology·Hyeon Jin LeeShinyoung Park
Jun 17, 2020·SA Journal of Radiology·Anjuna ReghunathApurva Surana
Mar 27, 2009·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Hyun Cheol KimSung Jig Lim
May 2, 2012·Acta Radiologica·Kian Soon LimCher Heng Tan
Nov 1, 2011·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Atul KapoorGoldaa Mahajan
Jun 27, 2020·World Journal of Gastroenterology : WJG·Mi Hye YuSung Il Jung
Nov 7, 2018·Journal of Gastrointestinal Cancer·Vikas GuptaK Vaiphei
Apr 24, 2020·Expert Review of Gastroenterology & Hepatology·Pankaj GuptaManavjit Singh Sandhu
Jan 3, 2021·Abdominal Radiology·Dhakshinamoorthy GaneshanCatherine Devine
Nov 13, 2020·World Journal of Gastroenterology : WJG·Pankaj GuptaManavjit Singh Sandhu
Jul 21, 2021·Journal of Korean Medical Science·Seong Ji ChoiDongho Choi

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