Analysis of etiology, chromosome and prognosis for small left heart system development in 69 fetuses

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Lin LiuLei Huang

Abstract

To provide a basis for evaluating the prognosis of small left heart system development in fetuses, we analyzed its related factors. The fetal echocardiogram was performed in 3859 pregnant women, and then small left heart system development was identified in 69 fetuses. The data of prenatal and postnatal echocardiograms, postnatal cardiac surgical treatment, chromosome and autopsy after induced labor were analyzed in the 69 fetuses. Except 1320 cases losing follow-up, 2539 cases had complete data. Among the 2539 cases, small left heart system development was identified in 69 fetuses. Of the 69 fetuses, 12 had hypoplastic left heart syndrome, 20 premature closure of foramen ovale, 13 total anomalous pulmonary venous drainage, 2 common pulmonary vein lumen atresia, 21 aortic coarctation or interruption and 1 right pulmonary hypoplasia. Among the 69 fetuses, chromosome abnormality was found in 7. There are many etiological factors causing small left heart system development. The prognosis is poor in the fetuses with hypoplastic left heart syndrome, common pulmonary vein lumen atresia, pulmonary hypoplasia, other malformations or/and chromosome abnormality. Fetal echocardiography combined with chromosome examination can provide impo...Continue Reading

References

Sep 1, 1995·Obstetrics and Gynecology·M R LauriaR Romero
Apr 5, 2001·Prenatal Diagnosis·A Roberts
Jun 29, 2004·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Jack RychikMary Van Der Veld
Nov 16, 2004·The American Journal of Cardiology·Mary T DonofrioWilliam B Moskowitz
Jan 4, 2007·Pediatrics·Bahaaldin AlsoufiChristopher A Caldarone
Jul 21, 2007·Journal of Paediatrics and Child Health·James TibballsJim Wilkinson
Apr 16, 2010·The Journal of Thoracic and Cardiovascular Surgery·Angela M KelleConstantine Mavroudis
Sep 30, 2010·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·L YeoS Hassan
Sep 30, 2010·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·L YeoS Hassan
Feb 10, 2011·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·S LuewanT Tongsong
Mar 3, 2011·Acta Paediatrica·Takamichi IshikawaTakehiko Ohzeki
Sep 13, 2011·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Gerda SchwedlerHans-Werner Hense
Oct 14, 2011·Circulation·Tain-Yen HsiaUNKNOWN Modeling of Congenital Hearts Alliance (MOCHA) Investigators
Feb 22, 2012·The Journal of Thoracic and Cardiovascular Surgery·James S TweddellUNKNOWN Pediatric Heart Network Investigators
Jul 17, 2012·The Journal of Thoracic and Cardiovascular Surgery·Nancy S GhanayemUNKNOWN Pediatric Heart Network Investigators
Oct 12, 2012·General Thoracic and Cardiovascular Surgery·Naoki YoshimuraSaori Nagura
Apr 9, 2013·Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual·Emile A Bacha
Jul 22, 2014·Journal of Cardiac Surgery·Massimo A PadalinoGiovanni Stellin

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Citations

Feb 5, 2016·Prenatal Diagnosis·Seung Mi LeeJong Kwan Jun
Jan 23, 2020·Scientific Reports·Flora Y WongDietmar Schranz

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