Analysis of fasting antroduodenal manometry in children

Digestive Diseases and Sciences
T TomomasaP E Hyman

Abstract

Antroduodenal manometry has been used to determine the pathophysiology associated with signs and symptoms of gastrointestinal motility disorders. The diagnostic value of antroduodenal manomentry has been limited by the paucity of data from normal children. In this study, we compared antroduodenal manometry findings from 95 patients with symptoms suggesting a gastrointestinal motility disorder to 20 control children. Phase III of the migrating motor complex (MMC) was less frequent in patients (P < 0.05), especially in those who required total parenteral nutrition (P < 0.001), than in controls. Abnormal migration of phase III and short intervals between phase IIIs were more frequent in patients than in controls (P < 0.01 and P < 0.05, respectively). During phase II, persistent low-amplitude contractions and sustained tonic-phasic contraction were found only in parenteral-nutrition-dependent children. Short or prolonged duration of phase III, absence of phase I following phase III, tonic contractions during phase III, low amplitude of phase III contractions in a single recording site and clusters of contractions or prolonged propagating contractions during phase II were not more frequent in patients than in controls. We conclude t...Continue Reading

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Citations

Nov 20, 1998·Journal of Pediatric Gastroenterology and Nutrition·C Di LorenzoP E Hyman
Sep 1, 1999·Journal of Pediatric Gastroenterology and Nutrition·C Di LorenzoP E Hyman
Nov 28, 2002·Journal of Pediatric Gastroenterology and Nutrition·Paul E HymanLonnie K Zeltzer
Sep 10, 2003·Journal of Pediatric Gastroenterology and Nutrition·Tsili ZangenPaul E Hyman
Jan 22, 2004·Journal of Pediatric Gastroenterology and Nutrition·Denesh K ChitkaraSamuel Nurko
Jul 31, 2008·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·F L ConnorC Di Lorenzo
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Sep 29, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Flavia IndrioRuggiero Francavilla
Sep 6, 2002·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·C Di LorenzoJ Taminiau
Nov 28, 2017·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·R RosenS Nurko
May 16, 2012·Journal of Pediatric Gastroenterology and Nutrition·Roberto GomezCarlo Di Lorenzo
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Sep 18, 2021·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Atchariya ChanpongNikhil Thapar
Jul 6, 2021·Journal of Pediatric Gastroenterology and Nutrition·Alisara DamrongmaneeAjay Kaul

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