PMID: 9007638Jan 1, 1996Paper

Analysis of fentanyl and sufentanil in hair by GC/MS/MS

International Journal of Legal Medicine
H SachsE Schneider

Abstract

Fentanyl and sufentanil are potent narcotic analgesics used only in hospitals as anaesthetic agents. The dependence potential of fentanyl is known. As they are given in doses at the microgram level and their elimination half-life is in the order of a few hours, detection in body fluids is possible only for a short time after administration. Radioimmunological methods are the only ones capable of detecting fentanyl in hair, as normal GC/MS methods for hair analysis are not sensitive enough to detect the drugs after doses in the order of micrograms. We therefore chose GC/MS/MS to analyse fentanyl and sufentanil in two cases where the drugs were given under controlled conditions over several days. The concentration was in the order of less than 100 pg/mg hair.

References

Jul 1, 1988·Journal of Analytical Toxicology·W R Hammargren, G L Henderson
Sep 1, 1993·Forensic Science International : Synergy·W L WangJ Zacny

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Citations

May 9, 2007·Analytical and Bioanalytical Chemistry·Frank Musshoff, Burkhard Madea
Nov 23, 2006·International Journal of Legal Medicine·Jörg TeskeMatthias Karst
Jan 17, 1997·Forensic Science International : Synergy·M Uhl
May 24, 2006·International Journal of Toxicology·Vassiliki A BoumbaTheodore Vougiouklakis
Nov 17, 2007·Forensic Science International : Synergy·C MooreK Crompton
Apr 21, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·Fritz Pragst, Marie A Balikova
Jan 25, 2006·Forensic Science International : Synergy·Elena F KraniotiManolis Michalodimitrakis
Jun 22, 2005·Forensic Science International : Synergy·P KintzV Cirimele
Feb 14, 1998·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·B H Anderton
Jun 27, 2015·Water Science and Technology : a Journal of the International Association on Water Pollution Research·Lin XuYulian Xiang
Jul 16, 2019·Forensic Sciences Research·Inês TabarraEugenia Gallardo
Nov 26, 1999·Journal of Chromatography. B, Biomedical Sciences and Applications·Y Nakahara

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