Analysis of Fgf15 expression pattern in the mouse neural tube

Brain Research Bulletin
L GimenoS Martínez

Abstract

The dynamic process of neural tube regionalization in vertebrates is regulated by the expression of developmental genes which appear in characteristic patterns at neuroepithelial transversal domains, which are called secondary organizers. The molecular code present in these neuroepithelial organizers controls the generation of morphogenetic signals that induce and maintain regional characteristics in the surrounding neuroepithelium. The product of the Fgf8 gene is a secreted protein that has been demonstrated to be the key molecule for the isthmic organizer and is also expressed in two other organizer regions: the zona limitans and the anterior neural ridge. Here we analyze the expression of Fgf15 at different stages of mouse development in relation to Fgf8 and Otx2 expression patterns.

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Citations

Oct 24, 2003·Brain Research. Brain Research Reviews·Diego EchevarríaSalvador Martínez
Aug 14, 2003·Gene Expression Patterns : GEP·L GimenoS Martínez
Feb 4, 2012·Genes & Development·Matthew J PotthoffDavid J Mangelsdorf
Jul 16, 2008·Neural Development·Ugo BorelloJohn L R Rubenstein
Aug 27, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Murat Burak YaylaogluGregor Eichele
Jul 27, 2007·Developmental Dynamics : an Official Publication of the American Association of Anatomists·L Gimeno, S Martinez
Dec 31, 2010·The Journal of Comparative Neurology·Asuka Suzuki-HiranoTomomi Shimogori
Oct 3, 2015·Seminars in Cell & Developmental Biology·Kathleen R Markan, Matthew J Potthoff
Jun 27, 2006·Gene Expression Patterns : GEP·Hortensia Sánchez-CalderónMatías Hidalgo-Sánchez
Apr 15, 2004·Developmental Biology·Tracy J WrightSuzanne L Mansour
Aug 21, 2018·Endocrine Reviews·Emmanuel Somm, François R Jornayvaz
Mar 11, 2003·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Rosanna Dono
May 19, 2020·The Journal of Comparative Neurology·Luis PuellesJohn L R Rubenstein
Dec 17, 2020·Frontiers in Neuroanatomy·Carmen Diaz, Luis Puelles
Mar 19, 2003·Development·Sonia GarelJohn L R Rubenstein
Aug 8, 2021·Nature Communications·Nadejda Bozadjieva-KramerRandy J Seeley

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