Analysis of Gafchromic EBT3 film calibration irradiated with gamma rays from different systems: Gamma Knife and Cobalt-60 unit

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists
Mohsen NajafiJavad Teimouri

Abstract

In recent years, Gafchromic films are used as an advanced instrument for dosimetry systems. The EBT3 films are a new generation of Gafchromic films. Our main interest is to compare the response of the EBT3 films exposed to gamma rays provided by the Theratron 780C as a conventional radiotherapy system and the Leksell Gamma Knife as a stereotactic radiotherapy system (SRS). Both systems use Cobalt-60 sources, thus using the same energy. However, other factors such as source-to-axis distance, number of sources, dose rate, direction of irradiation, shape of phantom, the field shape of radiation, and different scatter contribution may influence the calibration curve. Calibration curves for the 2 systems were measured and plotted for doses ranging from 0 to 40 Gy at the red and green channels. The best fitting curve was obtained with the Levenberg-Marquardt algorithm. Also, the component of dose uncertainty was obtained for any calibration curve. With the best fitting curve for the EBT3 films, we can use the calibration curve to measure the absolute dose in radiation therapy. Although there is a small deviation between the 2 curves, the p-value at any channel shows no significant difference between the 2 calibration curves. Therefor...Continue Reading

Citations

Sep 6, 2019·Physics in Medicine and Biology·Stewart BeckerByongYong Yi
Oct 3, 2020·The Review of Scientific Instruments·C B CurryS H Glenzer
Jan 21, 2021·Journal of Korean Neurosurgical Society·Beong Ik HurSoon Ki Sung
Jun 15, 2019·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Khaled SolimanAbdullah Alrushoud
Jul 17, 2021·Scientific Reports·Nurhaslina HasanMohammad Johari Ibahim

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