Analysis of globule types in malignant melanoma.

Archives of Dermatology
Jin XuM Emre Celebi

Abstract

To identify and analyze subtypes of globules based on size, shape, network connectedness, pigmentation, and distribution to determine which globule types and globule distributions are most frequently associated with a diagnosis of malignant melanoma. Retrospective case series of dermoscopy images with globules. Private dermatology practices. Patients in dermatology practices. Intervention Observation only. Main Outcome Measure Association of globule types with malignant melanoma. The presence of large globules (odds ratio [OR], 5.25) and globules varying in size (4.72) or shape (5.37) had the highest ORs for malignant melanoma among all globule types and combinations studied. Classical globules (dark, discrete, convex, and 0.10-0.20 mm) had a higher risk (OR, 4.20) than irregularly shaped globules (dark, discrete, and not generally convex) (2.89). Globules connected to other structures were not significant in the diagnosis of malignant melanoma. Of the different configurations studied, asymmetric clusters have the highest risk (OR, 3.02). The presence of globules of varying size or shape seems to be more associated with a diagnosis of malignant melanoma than any other globule type or distribution in this study. Large globules a...Continue Reading

References

Oct 1, 1993·Journal of the American Academy of Dermatology·A SteinerH Pehamberger
Dec 26, 2001·Archives of Dermatology·R Hofmann-WellenhofH P Soyer
Jun 21, 2002·Clinics in Dermatology·Ralph P BraunJean H Saurat
May 8, 2003·Journal of the American Academy of Dermatology·Giuseppe ArgenzianoAlfred W Kopf
Jan 1, 2005·Journal of the American Academy of Dermatology·Giuseppe Argenziano
Sep 20, 2006·Archives of Dermatology·Scott W Menzies, Iris Zalaudek
Feb 21, 2007·Archives of Dermatology·Alon ScopeAshfaq A Marghoob

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Citations

Dec 21, 2012·Pediatric Dermatology·Elena C HaliasosAshfaq A Marghoob
Jan 12, 2012·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Beibei ChengHarold S Rabinovitz
Dec 10, 2013·Computers in Biology and Medicine·Jose Luis García Arroyo, Begoña García Zapirain
Nov 19, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·O ReiterA A Marghoob

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