Analysis of growth rate in sucrose-supplemented cultures of Streptococcus mutans.

Infection and Immunity
L Daneo-MooreG D Shockman

Abstract

In the presence of sucrose, Streptococcus mutans grows in large glucan-containing aggregates. Because of reports of linear rather than exponential growth of sucrose-grown cultures, the kinetics of growth of sucrose-grown cultures of S. mutans strain OMZ-176 were compared with those of glucose-grown cultures. Culture turbidity measurements indicated that growth of sucrose cultures was slower, did not follow exponential kinetics, and slowed and stopped at lower absorbance values than did glucose-grown cultures. However, measurements of the rates of accumulation of deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and protein using fully equilibrated radioactively labeled precursors of each of these macromolecular species in sucrose and glucose-grown cultures showed that: (i) for glucose cultures the synthesis of each of the three informational molecules occurred at the same exponential rate, which was identical to the rate of turbidity increase; (ii) for sucrose cultures each macromolecular species was synthesized at the same exponential rate and these rates were identical to the rate of increase of turbidity of the glucose-grown culture for periods of up to 7 h. Furthermore, the ratios of DNA to RNA, RNA to protein, and prote...Continue Reading

References

Apr 1, 1975·Infection and Immunity·B TerleckyjG D Shockman
Mar 1, 1971·Journal of Bacteriology·G S RothL Daneo-Moore
Sep 1, 1969·Journal of General Microbiology·J M TanzerM I Krichevsky
Dec 1, 1957·Bacteriological Reviews·A CAMPBELL
Jan 1, 1961·Journal of Bacteriology·G D ShockmanG Toennies

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Citations

Jan 1, 1980·Scandinavian Journal of Infectious Diseases. Supplementum
Oct 7, 2004·Applied and Environmental Microbiology·John A RenyeBettina A Buttaro
Oct 29, 2015·Journal of Food Science·K M Maria John, Devanand Luthria
Apr 1, 1980·Antimicrobial Agents and Chemotherapy·M MychajlonkaG D Shockman
Jun 1, 1980·Microbiological Reviews·S Hamada, H D Slade

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