Analysis of hair after contamination with blood containing cocaine and blood containing benzoylecgonine

Forensic Science International : Synergy
Sue PatersonRosa Cordero

Abstract

In post-mortem work, blood is a potential source of external contamination of hair. The present study was carried out to investigate the amount of drug absorbed into hair which has been contaminated with blood containing either cocaine or BE. Solutions were prepared containing 0.05, 0.1, 0.2, 0.5 and 3.0 microg/mL of either cocaine or BE in human blood. Samples of approximately 3.2g of drug-free hair were contaminated by soaking in the blood solutions for 5 min. They were then removed and left at room temperature. Approximately 0.5 g of hair was collected from each of the blood soaked hair samples at 6h, 1, 2, 4 and 7 days after contamination. As each hair sample was collected it was shampoo-washed to prevent further drug absorption. Hair samples were analysed in triplicate using a fully validated method described previously. EME and cocaethylene were also measured in order to find out if cocaine or BE was breaking down to these compounds. Both cocaine and BE were absorbed into hair in significant concentrations when the concentration in the blood was 0.5 microg/mL or greater; cocaine was more readily absorbed than BE. Cocaine broke down to EME (<LOQ) at 0.5 microg/mL and to EME (>LOQ) and BE (<LOQ) at 3.0 microg/mL. When the b...Continue Reading

References

Dec 1, 2001·Forensic Science International : Synergy·G RomanoI Lombardo
Jan 17, 2004·Clinical Chemistry·Jana ThorspeckenLucia Pötsch
Jan 11, 2007·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Rosa Cordero, Sue Paterson
Jun 21, 2007·Journal of Analytical Toxicology·John F Casale

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Citations

Aug 8, 2014·Journal of Analytical Toxicology·Cynthia L Morris-KukoskiRena L Hammer
Mar 12, 2011·Forensic Science International : Synergy·Sue PatersonRosa Cordero
Sep 11, 2010·Forensic Science International : Synergy·Sooyeun LeeKyu Hyuck Chung
Aug 14, 2019·Drug Testing and Analysis·Dylan MantinieksDimitri Gerostamoulos
Jul 5, 2018·Forensic Science, Medicine, and Pathology·Dylan MantinieksOlaf Drummer
May 3, 2011·Analytical Chemistry·T A BrettellJ R Almirall

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