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Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy

Scientific Reports

Aug 19, 2019

Ratna VeeramachaneniNalin S Thakker

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Abstract

We report changes in the genomic landscape in the development of head and neck squamous cell carcinomas HNSCC from potentially premalignant lesions (PPOLS) to malignancy and lymph node metastases. Likely pathological mutations predominantly involved a relatively small set of genes repor...read more

Mentioned in this Paper

Malignant Neoplasms
Gene Deletion
Genes
Genome
Head
Neoplasm Metastasis
Protein p53
Cell Line, Tumor
Promoter
Rac1 GTP-Binding Protein
15
7
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Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy

Scientific Reports

Aug 19, 2019

Ratna VeeramachaneniNalin S Thakker

PMID: 31427592

DOI: 10.1038/s41598-019-48229-7

Abstract

We report changes in the genomic landscape in the development of head and neck squamous cell carcinomas HNSCC from potentially premalignant lesions (PPOLS) to malignancy and lymph node metastases. Likely pathological mutations predominantly involved a relatively small set of genes repor...read more

Mentioned in this Paper

Malignant Neoplasms
Gene Deletion
Genes
Genome
Head
15
7

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Paper Details
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