Analysis of HIV-1 BF pr/rt recombinant strains from Rio de Janeiro/Brazil reveals multiple unrelated mosaic structures

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases
Monick L GuimaraesMariza G Morgado

Abstract

Due to the co-circulation of HIV-1 subtypes B and F1 in Brazil, a large variety of unique BF1 recombinant forms (URFs_BF1) and four circulating BF1 recombinant forms (CRF28, CRF29, CRF39 and CRF40) have been described. The aim of this study was to investigate mosaic structure and phylogenetic relationship among several BF1 (protease-reverse transcriptase, pr/rt) recombinant sequences obtained from a group of patients from Rio de Janeiro, Brazil, from 1994 to 2005. Phylogenetic relationships were estimated by Bayesian and SplitsTree methods. Recombination breakpoints were analyzed by Bootscan. Those samples presenting the same recombinant pattern in the pr/rt region were investigated in the integrase (int) and envelope (env) regions as a screening method for the detection of potential new CRFs candidates. Third out of 61 pr/rt HIV-1 BF1 recombinant sequences analyzed depicted unique recombinant structures and were classified URFs_BF1. The other 31 samples segregated in eight well-supported phylogenetic clusters composed of at least three samples sharing the same recombination pattern. Analyses of the int and env regions from these 31 samples revealed that 11 samples were URFs_BF1. Three and four sequences corresponded, respectiv...Continue Reading

References

Nov 1, 1995·AIDS Research and Human Retroviruses·M O SalminenF E McCutchan
Jun 3, 2000·Journal of Acquired Immune Deficiency Syndromes : JAIDS·A C VicenteA Tanuri
Dec 19, 2002·AIDS Research and Human Retroviruses·Monick Lindenmeyer GuimarãesUNKNOWN Brazilian Network for HIV Isolation and Characterization
Apr 18, 2003·AIDS·Rodrigo M BrindeiroUNKNOWN Brazilian Network for Drug Resistance Surveillance
Aug 13, 2003·Bioinformatics·Fredrik Ronquist, John P Huelsenbeck
Oct 14, 2005·Molecular Biology and Evolution·Daniel H Huson, David Bryant
Jan 28, 2006·AIDS Research and Human Retroviruses·Dercy José De Sá FilhoLuiz Mario Janini
Mar 4, 2006·AIDS·Gonzalo BelloMariza G Morgado
Mar 17, 2006·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Claudia C BarretoEster C Sabino
Apr 22, 2006·Journal of Medical Virology·Sylvia Lopes Maia TeixeiraMariza Gonçalves Morgado
Dec 8, 2006·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Gonzalo BelloMariza G Morgado
Feb 13, 2007·Memórias do Instituto Oswaldo Cruz·Valéria P CabralRodrigo Ribeiro-Rodrigues
Mar 3, 2007·AIDS Research and Human Retroviruses·Walter A Eyer-SilvaMariza G Morgado
Apr 26, 2007·Journal of Medical Virology·Maritza RíosRafael Nájera
May 10, 2007·Molecular Biology and Evolution·Koichiro TamuraSudhir Kumar
Jun 1, 2007·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Mariane M A StefaniAparecida Hg Mussi
Oct 27, 2007·AIDS Research and Human Retroviruses·Dario A DilerniaManuel Gómez-Carrillo
Dec 28, 2007·AIDS Research and Human Retroviruses·Nazle M C VérasCláudia R F Martins
Jan 11, 2008·AIDS Research and Human Retroviruses·Catherine A BrennanRoberto Badaro
Jan 16, 2008·AIDS·Monick L GuimarãesMariza G Morgado
Mar 11, 2008·AIDS Research and Human Retroviruses·Dercy José de Sa-FilhoMarcos Montani Caseiro
Nov 26, 2008·AIDS Research and Human Retroviruses·Ana Carolina Mamana Fernandes de SouzaJosé Eduardo Levi
Mar 31, 2009·AIDS Research and Human Retroviruses·Dora RuchanskyCecilio Lopez-Galindez
May 23, 2009·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Caroline Pereira Bittencourt PassaesMonick Lindenmeyer Guimarães
Aug 18, 2009·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Ludimila Paula Vaz CardosoMariane Martins de Araújo Stefani

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Citations

Aug 31, 2013·AIDS Research and Human Retroviruses·Victor F PimentelMonick L Guimarães
Jan 18, 2012·Virology Journal·Monick L GuimarãesMariza G Morgado
Dec 14, 2011·AIDS Research and Treatment·Gonzalo BelloCarlos G Schrago
Jun 14, 2018·Memórias do Instituto Oswaldo Cruz·Bianca Cristina Leires MarquesMonick Lindenmeyer Guimarães
Jun 20, 2017·PloS One·Mônica Nogueira da Guarda ReisMariane Martins Araújo Stefani
Sep 24, 2020·BioMed Research International·Lada V MaksimenkoNatalya M Gashnikova

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