PMID: 9544239Apr 17, 1998Paper

Analysis of HLA class I and class II in Na-Dene and Amerindian populations from British Columbia, Canada

Human Immunology
M V MonsalveD V Devine

Abstract

We analyzed the distribution of HLA class II alleles and haplotypes in one Na-Dene (Athabaskan) group from British Columbia (Canada) by PCR amplification of the DRB1, DQA1 and DQB1 second exon sequences. We extended the typing of the DRB1 in an Amerindian group (Penutian) from British Columbia. The presence of the alleles DRB1* 0405, *0407 and *0410 only in Na-Dene and alleles DRB1*0408, *1301*1302, *1304, *1305, *1502 and *1601 only in Amerindians suggests separate origins of these two groups. There were fifteen different DRB1/DQA1/DQB1 haplotypes. One unique haplotype previously reported in Native Americans was found. Thirty-four per cent of Athabaskans presented Native American haplotype DRB1*1402/DQA1*0501/DQB1*0301. In addition, the results of this study are compatible with previous evidence with mitochondrial (mtDNA) polymorphisms indicating that Amerindians and Na-Dene populations derived from different migrations from Asia.

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Citations

Jun 23, 1999·American Journal of Physical Anthropology·J L RupertP W Hochachka
Jun 22, 2000·American Journal of Physical Anthropology·V S MatteviM H Hutz
Mar 15, 2006·European Journal of Medical Genetics·Jorge Martinez-LasoAntonio Arnaiz-Villena
Sep 16, 2000·Current Opinion in Rheumatology·K Oen
Jan 29, 2000·Proceedings. Biological Sciences·M V MonsalveD V Devine
Jun 14, 2012·PloS One·Manon Ragonnet-CroninJames Brooks
Nov 7, 1999·Tissue Antigens·J Bruges-ArmasA Arnaiz-Villena
Mar 11, 2004·European Journal of Immunogenetics : Official Journal of the British Society for Histocompatibility and Immunogenetics·T S Uinuk-OolR I Sukernik
Jun 6, 2009·International Journal of Immunogenetics·A Arnaiz-VillenaJ Moscoso
Aug 19, 2015·Immunological Reviews·Raphael Carapito, Seiamak Bahram
Sep 26, 2014·Immunological Investigations·Antonio Arnaiz-VillenaDiego Rey
Jul 6, 2002·Anais Da Academia Brasileira De Ciências·Francisco M Salzano
Dec 30, 2010·Genetic Testing and Molecular Biomarkers·Antonio Arnaiz-VillenaGilberto Vargas-Alarcón
Jul 14, 2007·International Journal of Immunogenetics·S AgrawalU Bharadwaj
Oct 7, 2010·Immunological Investigations·Carlos SilveraAntonio Arnaiz-Villena
Jun 26, 2003·Tissue Antigens·E Gómez-CasadoA Arnaiz-Villena
Apr 13, 2010·Immunological Investigations·Gilberto Vargas-AlarcónAntonio Arnaiz-Villena
Oct 7, 2010·Immunological Investigations·Gilberto Vargas-AlarcónAntonio Arnaiz-Villena
May 15, 2013·Molecular Biology Reports·Diego ReyAntonio Arnaiz-Villena
Aug 23, 2005·Molecular Immunology·Gilberto Vargas-AlarcónAntonio Arnaiz-Villena

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