Analysis of Interactions between Telomeric i-Motif DNA and a Cyclic Tetraoxazole Compound

Chembiochem : a European Journal of Chemical Biology
Shadi Sedghi MasoudKazuo Nagasawa

Abstract

The interaction of a macrocyclic tetraoxazole compound, L2H2-4OTD (1), with two aminoalkyl side chains and telomeric i-motif, was investigated by means of electrophoretic mobility shift assay, circular dichroism spectroscopy, mass spectrometry and NMR spectroscopy analyses. The results indicate that 1 interacts with the i-motif structure at two preferred binding sites.

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Citations

Nov 9, 2018·Angewandte Chemie
Jan 3, 2019·Angewandte Chemie·Manish DebnathJyotirmayee Dash
Dec 7, 2018·Chemical & Pharmaceutical Bulletin·Shadi Sedghi Masoud, Kazuo Nagasawa
Mar 8, 2020·Biophysics Reviews·Yudai YamaokiMasato Katahira
Oct 29, 2020·Biophysics and Physicobiology·Yudai YamaokiMasato Katahira
Jul 3, 2021·Cancers·Victoria Sanchez-MartinJose Antonio Garcia-Salcedo
Aug 12, 2021·Chemical Science·Changpeng HuHanbin Mao
Oct 1, 2021·Chemical Reviews·Eric LargyValérie Gabelica

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