Analysis of major proteins and fat fractions associated with mare's milk fat globules

Molecular Nutrition & Food Research
Cristina BarelloMaria Gabriella Giuffrida

Abstract

Although several studies have aimed to identify mare's milk proteins, only the major whey proteins and some caseins have yet been characterized. Incomplete sequencing of the equine genome and the difficulty of recovering highly hydrophobic proteins mean that little is known to date about the proteins associated with milk fat globules, which have been shown to play an important role in newborns' defense mechanisms. The fat fraction, in particular the distribution of unsaturated fatty acids, has been more extensively studied, but complex lipids are only partially elucidated. This study reports a 2-DE approach combined with a powerful method for de novo protein sequencing, and quali-quantitative data on complex lipid composition determined by high performance TLC (HPTLC) and GC. The presence in mare's milk of long-chain highly unsaturated fatty acids, and the evidence of close similarity between equine and human milk fat globule membrane proteins, support the use of mare's milk for human nutrition.

References

Apr 1, 1987·Biological Chemistry Hoppe-Seyler·J Godovac-ZimmermannH McKenzie
Dec 1, 1984·Hoppe-Seyler's Zeitschrift für physiologische Chemie·A ContiG Braunitzer
Jan 18, 1980·Biochimica Et Biophysica Acta·L Svennerholm, P Fredman
Nov 1, 1994·Cell Biology International·A M RizzoB Berra
Dec 1, 1995·Biological Chemistry Hoppe-Seyler·R RuedaA Gil
May 16, 2000·The Journal of Allergy and Clinical Immunology·L BusincoM Orlandi
Sep 22, 2001·The American Journal of Clinical Nutrition·B WangP Petocz
Feb 8, 2003·Biochimica Et Biophysica Acta·Ladislas ColarowAlvin Berger
Jul 2, 2003·Proteomics·Donatella FortunatoAmedeo Conti
Jul 2, 2003·Proteomics·Enrica PessioneCarlo Giunta
Jul 27, 2004·Proteomics·Guy MirandaPatrice Martin
Aug 18, 2004·Clinica Chimica Acta; International Journal of Clinical Chemistry·Maria CavalettoAmedeo Conti
Oct 7, 2004·Glycoconjugate Journal·Koichi HonkeNaoyuki Taniguchi
Apr 1, 2006·Glycoconjugate Journal·Pavel IsaSusana López
Jul 13, 2006·The Journal of Dairy Research·Timothy A Reinhardt, John D Lippolis
Oct 27, 2006·Biology of the Cell·Vera Michel, Marica Bakovic
Feb 28, 2007·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·William S Harris

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Citations

Sep 9, 2009·Journal of Medicinal Food·S ZavaM G Giuffrida
Sep 25, 2014·Reproduction in Domestic Animals = Zuchthygiene·M BazzanoG Piccione
Feb 23, 2010·Journal of Dairy Science·C CeboP Martin

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