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Analysis of mannose receptor regulation by IL-4, IL-10, and proteolytic processing using novel monoclonal antibodies

Journal of Leukocyte Biology

Apr 26, 2003

Luisa Martinez-PomaresSimon Y C Wong

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Abstract

The study of the murine macrophage mannose receptor (MR) has been hampered by the lack of specific reagents. We have generated and characterized novel anti-MR monoclonal antibodies and used them to analyze MR expression in primary mouse macrophages (M(phi)). In BioGel- and thioglycollat...read more

Mentioned in this Paper

Macrophages, Peritoneal
Cricetulus
Interleukins
Monoclonal Antibodies
Immune Response
Monoclonal antibodies, antineoplastic
Flow Cytometry
CD206 antigen
Endocytosis
Mice, Inbred BALB C
63
Paper Details
References
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  • Citations63
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  • References32
  • Citations63
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Analysis of mannose receptor regulation by IL-4, IL-10, and proteolytic processing using novel monoclonal antibodies

Journal of Leukocyte Biology

Apr 26, 2003

Luisa Martinez-PomaresSimon Y C Wong

PMID: 12714575

DOI: 10.1189/jlb.0902450

Abstract

The study of the murine macrophage mannose receptor (MR) has been hampered by the lack of specific reagents. We have generated and characterized novel anti-MR monoclonal antibodies and used them to analyze MR expression in primary mouse macrophages (M(phi)). In BioGel- and thioglycollat...read more

Mentioned in this Paper

Macrophages, Peritoneal
Cricetulus
Interleukins
Monoclonal Antibodies
Immune Response
Monoclonal antibodies, antineoplastic
Flow Cytometry
CD206 antigen
Endocytosis
Mice, Inbred BALB C
63

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Immune Therapies In Cancer

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Endocytic System

Adsorptive and receptor-mediated endocytosis via clathrin-coated vesicles provides the major and best-characterized portal for uptake of multiple molecules and particles into cells. Via clathrin-dependent endocytosis, cells receive nutrients, regulate receptors and other plasma membrane constituents, take up antigens, and remove senescent, excess, and potentially harmful substances from the extracellular fluid. Discover the latest research on endocytic system here.

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Paper Details
References
  • References32
  • Citations63
1234
  • References32
  • Citations63
12345...

Download from

Publisher
PubMed
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