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Analysis of miRNA expression profiles in the liver of ClockΔ19 mutant mice

PeerJ

Dec 5, 2019

Yanli WangLina Qu

Abstract

The circadian clock controls the physiological functions of many tissues including the liver via an autoregulatory transcriptional-translational feedback loop, of which CLOCK is a core positive component. In addition, many studies have indicated that microRNAs (miRNAs) regulate liver fu...read more

Mentioned in this Paper

Study
Biochemical Pathway
AKT1
Genes
MIR340
Transcription, Genetic
Mutant Proteins
CLOCK Proteins
NR1D2 gene
Biological Clocks
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Analysis of miRNA expression profiles in the liver of ClockΔ19 mutant mice

PeerJ

Dec 5, 2019

Yanli WangLina Qu

PMID: 31799078

DOI: 10.7717/peerj.8119

Abstract

The circadian clock controls the physiological functions of many tissues including the liver via an autoregulatory transcriptional-translational feedback loop, of which CLOCK is a core positive component. In addition, many studies have indicated that microRNAs (miRNAs) regulate liver fu...read more

Mentioned in this Paper

Study
Biochemical Pathway
AKT1
Genes
MIR340
Transcription, Genetic
Mutant Proteins
CLOCK Proteins
NR1D2 gene
Biological Clocks

Similar Papers Found In These Feeds

RNAi & Gene Silencing

RNA Interference (RNAi) pathway is involved in post-transcriptional gene silencing, transcriptional silencing and epigenetic silencing as well as its use as a tool for forward genetics and therapeutics. Discover the latest research here.

Circadian Clock & Cancer

Circadian rhythms are natural, internal processes that regulate the sleep-wake cycle. Chronic disruptions in circadian rhythms have been associated with the development of a variety of diseases including cancer. Here is the latest research on circadian rhythms and cancer.

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