Analysis of myocardial injury in patients with COVID-19 and association between concomitant cardiovascular diseases and severity of COVID-19

Zhonghua xin xue guan bing za zhi
C ChenD W Wang

Abstract

Objective: To evaluate the cardiovascular damage of patients with COVID-19, and determine the correlation of serum N-terminal pro B-type natriuretic peptide (NT-proBNP) and cardiac troponin-I (cTnI) with the severity of COVID-19, and the impact of concomitant cardiovascular disease on severity of COVID-19 was also evaluated. Methods: A cross-sectional study was designed on 150 consecutive patients with COVID-19 in the fever clinic of Tongji Hospital in Wuhan from January 19 to February 13 in 2020, including 126 mild cases and 24 cases in critical care. Both univariate and multivariate logistic regression were used to analyze the correlation of past medical history including hypertension, diabetes and coronary heart disease (CHD), as well as the levels of serum NT-proBNP and cTnI to the disease severity of COVID-19 patients. Results: Age, hypersensitive C-reactive protein(hs-CRP) and serum creatinine levels of the patients were higher in critical care cases than in mild cases(all P<0.05). Prevalence of male, elevated NT-proBNP and cTnI, hypertension and coronary heart disease were significantly higher in critical cases care patients than in the mild cases(all P<0.05). Univariate logistic regression analysis showed that age, male...Continue Reading

Associated Clinical Trials

Citations

Jun 1, 2020·European Journal of Pediatrics·Giulia SannaMaria Antonietta Marcialis
Jun 9, 2020·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·Skand ShekharFady Hannah-Shmouni
Jun 26, 2020·Frontiers in Medicine·Xudong FengGuodong Cao
Aug 28, 2020·Frontiers in Pharmacology·Inés ValenciaTania Romacho
Aug 23, 2020·International Journal of Environmental Research and Public Health·Karla Romero StarkeAndreas Seidler
Oct 3, 2020·International Journal of Molecular Sciences·Eileen M McGowanYiguang Lin
Apr 25, 2020·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Gerui LiJinping Lu
Sep 3, 2020·Diabetology & Metabolic Syndrome·Bianca de Almeida-PitittoUNKNOWN Brazilian Diabetes Society Study Group (SBD)
Oct 17, 2020·SN Computer Science·Md Milon IslamSafial Islam Ayon
Dec 18, 2020·Frontiers in Physiology·Puneet Kaur RandhawaManish K Gupta
Nov 3, 2020·World Journal of Diabetes·Min DuJue Liu
Dec 4, 2020·World Journal of Clinical Cases·Moises Rodriguez-GonzalezAlvaro Antonio Perez-Reviriego
Mar 6, 2021·Frontiers in Cardiovascular Medicine·Yonghao LanYujie Zhou
Mar 4, 2021·Scientific Reports·Aakash ShethPaari Dominic
Apr 6, 2021·Journal of Cardiovascular and Thoracic Research·Fatemeh SadoughiBahman Yousefi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disorder in Diabetes

Diabetes is associated with an increased risk of cardiovascular disorders and heart failure. Discover the latest research here.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Related Papers

Nature Reviews. Cardiology
Ying-Ying ZhengXiang Xie
The Lancet Oncology
Hanping Wang, Li Zhang
Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes
Wei-Cai DaiFan Lin
Tropical Medicine & International Health : TM & IH
Thirumalaisamy P Velavan, Christian G Meyer
© 2021 Meta ULC. All rights reserved