Analysis of prognostic factors associated with injection-site sarcomas in cats: 57 cases (2001-2007)

Journal of the American Veterinary Medical Association
Giorgio RomanelliEric Zini

Abstract

To identify prognostic factors in cats with injection-site sarcomas (ISSs). Retrospective case series. 57 cats with ISSs. Medical records of cats were reviewed with regard to sex, age, anatomic site of tumor, tumor size, histologic grade, excision of a primary tumor versus excision of a recurrent ISS, use of excision alone versus excision plus adjuvant therapy, local tumor recurrence, and development of distant metastasis to predict overall survival time (ie, time from tumor excision to death). In univariate analyses, local recurrence and development of distant metastasis were significantly associated with survival time in cats. On multivariate analysis, development of distant metastasis remained a significant prognostic factor. Histologic grade was associated with distant metastasis, with cats having grade 3 tumors being significantly more likely to develop metastasis than cats with grade 1 and 2 tumors. Factors associated with local recurrence of ISSs were not identified. The development of distant metastasis, which may occur later during the course of the disease, was identified as a prognostic factor for overall survival time in cats with ISSs. In addition, cats with histologic grade 3 ISSs should be considered for further ...Continue Reading

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Jun 4, 2008·Journal of the American Veterinary Medical Association·Peter Rowland
Jul 17, 2008·Journal of the American Veterinary Medical Association·F Yvonne Schulman
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