PMID: 16519826Mar 8, 2006Paper

Analysis of prognostic factors in patients with transitional cell carcinoma of the bladder treated with radical cystectomy

International Braz J Urol : Official Journal of the Brazilian Society of Urology
Alberto A AntunesMiguel Srougi

Abstract

To analyze the results of the treatment of transitional cell carcinoma (TCC) of the bladder with radical cystectomy and determine which prognostic factors can be utilized as disease-free survival and cancer-specific survival independent variables. Medical records of 113 patients submitted to radical cystectomy and bilateral iliac lymphadenectomy between 1993 and 2005 were reviewed. The risk factors analyzed were age, sex, pathological stage, tumor grade, presence of carcinoma in situ and the presence of lymph nodes involvement. After a mean follow-up of 31.7 +/- 28.5 months, 46 patients (40.7%) presented recurrence and 24 patients (21.2%) died due to cancer. Only pathological stage and the lymph nodes involvement became independent variables for recurrence and survival. Patients with T4 stage presented 9.6 times the risk of recurrence of the disease when compared with stage T0 patients (p = 0.010) and the patients with lymph node involvement presented 2.5 times the risk of recurrence (p = 0.047) and 3.1 times the risk of death (p = 0.022) when compared to patients without lymph nodes involvement. Pathological stage and the involvement of lymph nodes represented more important prognostic variables, and in the presence of advance...Continue Reading

References

Apr 15, 2005·International Journal of Urology : Official Journal of the Japanese Urological Association·Ken-Ichi HaradaHideaki Miyake

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Citations

Mar 23, 2011·Cellular Oncology (Dordrecht)·Susanne Schulze, Iver Petersen
May 16, 2013·Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·Catarina Pinto ReisLia Ascensão
Apr 10, 2010·Health Education Research·Alison NelsonDoune Macdonald
Jun 16, 2006·Inhalation Toxicology·Arkadiusz MoskalLeon Gradoń
Oct 17, 2012·International Journal of Pharmaceutical Investigation·Anil Kumar SinghalAnwar Daud
Sep 15, 2020·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association·Maíra Barbosa CoutinhoAnya Pimentel Gomes Fernandes Vieira-Meyer

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