PMID: 9171743May 1, 1997Paper

Analysis of randomized controlled trials in laparoscopic surgery

The British Journal of Surgery
K SlimJ Chipponi

Abstract

Randomized controlled studies of surgical procedures are difficult, but can be done to acceptable standards. There are few published objective assessments of such trials. The original articles that involved a randomized controlled trial including at least one laparoscopic procedure were reviewed and evaluated with special interest in their methodology. An assessment form containing 11 generic questions and three additional criteria (assessment of quality of life, cost analysis and laparoscopic experience required) was used. Forty trials were retrieved including 12 on cholecystectomy, 12 on hernia repair and 12 on appendicectomy. Each trial was scored by two assessors. The agreement among the two independent assessors was very good. Six of the trials were well conducted but 22 had a poor score. The trials on cholecystectomy were scored the best in contrast to those on hernia repair or appendicectomy. Few trials provided an adequate prospective calculation of the sample size, an unbiased assessment of endpoints, evaluation of the quality of life and a study of the economic aspects. Readers should be cautious when interpreting the results of some of these trials and their impact on daily surgical practice.

References

Jan 20, 1990·Lancet·D G Altman, C J Doré
Mar 11, 1991·Archives of Surgery·W Lawrence
May 1, 1990·Annals of Internal Medicine
Jun 1, 1990·American Journal of Surgery·J M Yancey
Oct 6, 1989·JAMA : the Journal of the American Medical Association·A S Detsky
Jun 3, 1982·The New England Journal of Medicine·R DerSimonianF Mosteller
May 1, 1981·Controlled Clinical Trials·T C ChalmersA Ambroz
Jul 1, 1995·American Journal of Surgery·M J Moore, C L Bennett
Oct 22, 1994·Lancet·A G Johnson
Sep 1, 1994·The British Journal of Surgery·K LawrenceP Morris
Jul 1, 1994·Surgical Endoscopy·B V MacFadyen, S Lenz
Jul 13, 1994·JAMA : the Journal of the American Medical Association·D MoherG A Wells
Aug 1, 1993·The British Journal of Surgery·A V Pollock
Jan 1, 1993·Diseases of the Colon and Rectum·M J Solomon, R S McLeod
Feb 1, 1993·The British Journal of Surgery·S C Fraser
May 1, 1996·Surgery·R S McLeodA l Lossing
Feb 1, 1996·American Journal of Surgery·M S LiemT J van Vroonhoven
Apr 1, 1996·Surgery·J C HallJ L Hall
Jun 1, 1996·Endoscopy·J D Mellinger, J L Ponsky

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Citations

Mar 26, 1998·Diseases of the Colon and Rectum·K SlimJ Chipponi
Apr 14, 2005·World Journal of Surgery·Karem Slim
Jul 5, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Hossein MasoomiMichael J Stamos
Oct 1, 2009·The Indian Journal of Surgery·Rajendra Desai, Bahaman N Shokouhi
Aug 2, 2012·The Indian Journal of Surgery·Anjan Kumar Das
Mar 16, 2000·The British Journal of Surgery·V L Wills, D R Hunt
Apr 12, 2005·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Daniel H W LauMichael K W Li
Apr 16, 1998·Equine Veterinary Journal·D St John Collier, S E Palmer
May 28, 2013·Canadian Journal of Surgery. Journal Canadien De Chirurgie·Forough FarrokhyarMohit Bhandari
Jun 24, 2005·Journal of Zhejiang University. Science. B·Li ChenShu-you Peng
Dec 25, 2007·Wiener klinische Wochenschrift·Heinz F Wykypiel, Raimund Margreiter
Sep 12, 2000·Current Gastroenterology Reports·T R Eubanks, C A Pellegrini
Jul 10, 2001·Surgical Endoscopy·C R Finley, J B McKernan
Jul 8, 2011·Digestive Diseases and Sciences·K T ParkJohn A Kerner
Dec 3, 2009·Gastrointestinal Endoscopy Clinics of North America·Timothy A WoodwardMichael B Wallace
Jan 21, 2012·Acta Anaesthesiologica Scandinavica·M A TolverT Bisgaard
Aug 1, 2006·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Vasu Karri
Mar 14, 2009·The British Journal of Surgery·K S GurusamyB R Davidson
Feb 16, 2010·The British Journal of Surgery·K Rerkasem, P M Rothwell
Sep 12, 1998·Lancet·K SlimJ Chipponi
Sep 10, 2016·Scandinavian Journal of Gastroenterology·Jian-Shan CaiYin Bao-Bing
Jun 23, 2004·International Journal of Clinical Practice·P DasguptaS Khan
Jun 25, 2004·Neurosurgery·George VranosJohn P A Ioannidis
Oct 26, 2005·Annales de chirurgie·R Flamein, K Slim
Oct 31, 2001·Anesthesiology·H L PuaJ G Wright
Feb 13, 2001·The Australian and New Zealand Journal of Surgery·M Zib, J Gani

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