Analysis of sulfonamides by capillary electrophoresis

Journal of Separation Science
Rodrigo Hoff, Tarso B L Kist

Abstract

The methods of analysis of sulfonamides (SFAs) using CE are reviewed. Sulfonamides were the first antimicrobial group of drugs used in medical treatment. These compounds are still used today in medicine and widely are employed in veterinary medicine, also for their growth promoter effects. Improved methods of analysis of sulfonamides are a constant challenge for researchers. CE is a new trend in the fields of pharmaceutical and food analyses. Several methods for the determination of SFAs by CE have been published in recent years, and the present review considers applications in quality control of pharmaceutical dosage forms, food analysis, determinations in serum, and other biological fluids as well as in electrophoresis experiments which examine the behavior of this class of compounds for theoretical studies of the technique. This review covers studies ranging from the pioneering works on sulfonamide analyses using classical electrophoresis to the more recent CE methods coupled to tandem mass spectrometers. The sections are divided following the EC modes like CZE, MEKC, and hyphenated methods (CE-MS, CE-MS/MS). A brief compilation of theoretical findings of sulfonamides electrophoretic behavior is also included. Parameters suc...Continue Reading

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Citations

Mar 8, 2012·Environmental Monitoring and Assessment·Yumei ChenAmmaiyappan Selvam
Oct 22, 2011·Journal of Pharmaceutical and Biomedical Analysis·N'Cho Christophe AminHuguette Fabre
Sep 24, 2013·Food Chemistry·Natalia Arroyo-ManzanaresAna M García-Campaña
Jan 1, 2010·Biotechnology & Genetic Engineering Reviews·Marco Van Den BergIda Vander Keli

Related Concepts

Sulfonamides
Electrophoresis, Capillary
Blood Capillaries
Pharmacotherapy
Pharmaceutical Preparations
Medicine
Research
Research Personnel
Mass Spectrometry
Sulfonamides

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