PMID: 18202800Jan 19, 2008Paper

Analysis of the clinicopathological prognosis of stage IVb cervical carcinoma

Oncology Reports
Shin NishioYasuhiro Fujiwara

Abstract

The aim of this study was to evaluate the clinicopathological prognostic factors in patients with stage IVb cervical carcinoma (CC). All patients with stage IVb CC included in the study were diagnosed from 1997 to 2006 at the National Cancer Center Hospital. We retrospectively examined clinicopathological parameters in these patients, including the efficacy of chemotherapy. Survival was evaluated using Kaplan-Meier curve analysis and log-rank test. The independent prognostic factors found to be predictive of survival in univariate and multivariate analysis were evaluated using a Cox's proportional hazard model. Thirty-six patients (median age 54 years) were diagnosed with stage IVb CC. The median progression-free survival and overall survival were 3.8 and 11.1 months, respectively. As initial treatment, 4 patients underwent hysterectomy, 13 received chemotherapy, 17 received radiotherapy, and the remaining 2 patients refused treatment. A total of 21 patients received chemotherapy, of which 13 were initial cases, 7 were persistent/recurrence cases, and 1 was a postoperative adjuvant case; 15 patients were never treated with chemotherapy. On univariate analysis, poor performance status (PS) and non-chemotherapy groups were consid...Continue Reading

Citations

Oct 25, 2013·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Hee Seung KimNoh Hyun Park
Dec 17, 2011·Archives of Gynecology and Obstetrics·Jong Ha HwangJoo-Young Kim
Feb 1, 2012·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Wichai TermrungruanglertSurasak Taneepanichskul
Feb 12, 2017·International Journal of Cancer. Journal International Du Cancer·S Nicolás-PárragaUNKNOWN RIS HPV TT and HPV VVAP study groups

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